Journal of College of Physicians and Surgeons Pakistan (JCPSP), is the prestigious, peer reviewed monthly biomedical journal of the country published regularly since 1991. College of Physicians and Surgeons Pakistan is the parent body of this Journal.


The College of Physicians and Surgeons of Pakistan (CPSP) is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide credits to educational activities.

CPSP designates '3 AMA PRA Category 1 Credits' for review of the manuscript of an original study.


Important Announcement for Authors

"As a large number of case reports are awaiting publication, JCPSP has decided to stop acknowledging Case Reports for a certain period of time until the backlog is cleared. Therefore, case reports are regretted from processing".

Latest Articles
Volume 31 | Issue 4 | April 2021
Need for Clinical Guidelines for Management of Osteoporosis and Way Forward for Pakistan

By Aysha Habib Khan, Manju Chandran

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Effects of Preoperative Statin on the Frequency of Ventricular Fibrillation and C-Reactive Protein Level in Patients Undergoing Isolated Coronary Artery Bypass Grafting

By Tufan Okumus, Arda Aybars Pala, Temmuz Taner, Ufuk Aydin

ABSTRACT Objective: To investigate the effects of statin use in preoperative period on the development of ventricular fibrillation (VF) following the removal of aortic cross-clamp (ACC) and on the levels of inflammation biomarker C-reactive protein (CRP) in patients who undergo elective isolated co...

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Relationship between First Values of Red Cell Distribution Width, Mean Platelet Volume, Platelet Distribution Width, and Hospital Mortality in Acute Deep Venous Thrombosis

By Sonay Oğuz

ABSTRACT Objective: To determine the relationship between red cell distribution width (RDW), mean platelet volume (MPV), platelet distribution width (PDW) values and mortality in acute deep vein thrombosis (DVT). Study Design: Descriptive study. Place and Duration of Study: Canakkale Onsekiz Mart Un...

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Diagnostic Accuracy of Serum Procalcitonin (PCT) as an Early Biomarker of Neonatal Sepsis using Blood Culture as Gold Standard

By Aisha Habib, Saba Raza, Usman Ali, Adnan Mustafa Zubairi, Erum Salim

ABSTRACT Objective: To ascertain the diagnostic accuracy of serum PCT as an early biomarker of neonatal sepsis using blood culture as gold standard, so that the condition could be diagnosed and managed early to prevent and reduce morbidity and mortality in neonates.  Study Design: Cross-sectio...

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CT Chest Severity Score for COVID 19 Pneumonia: A Quantitative Imaging Tool for Severity Assessment of Disease

By Sana Sayeed, Belqees Yawar Faiz, Samreen Aslam, Laiba Masood, Rohama Saeed

ABSTRACT Objective:  To determine a cut-off value of Chest CT severity score (CT-SS) in order to discriminate between the clinical types of COVID-19 pneumonia. Study Design: Observational study. Place and Duration of Study: Department of Radiology, Shifa International Hospital, from 1st March t...

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Vitamin D Levels and Vitamin D Receptor (VDR) Gene Polymorphisms in Inactive Hepatitis B Virus Carriers

By Suleyman Albas, Esra Meltem Koc, Salih Atakan Nemli, Tuna Demirdal, Mustafa Soyoz, Saliha Aksun, Melih Kaan Sozmen, Candeger Avsar, Burcu Cerci Gurbuz

ABSTRACT Objective: To evaluate the vitamin D receptor (VDR) gene polymorphisms and vitamin D levels in inactive hepatitis B virus (HBV) carriers. Study Design: A cross-sectional analytical study. Place and Duration of Study: From March to September 2017 at the Izmir Katip Celebi University (İKCU) ...

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Systemic Immune-inflammation Index (SII) Predicts Pathological Complete Response to Neoadjuvant Chemoradiotherapy in Locally Advanced Rectal Cancer

By Emrah Eraslan, Yasemin Guzle Adas, Fatih Yildiz, Aysegul Ilhan Gulesen, Cengiz Karacin, Ulku Yalcintas Arslan

ABSTRACT Objective: To determine the relationship between inflammatory markers and pathological complete response (pCR) in patients with locally advanced rectal cancer (LARC), who received neoadjuvant chemoradiotherapy (NACRT). Study Design: Descriptive study. Place and Duration of Study: Department...

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The Predictive Value of First-trimester Thiol/Disulfide Homeostasis in Preeclampsia

By Habibe Ayvaci Tasan, Gultekin Adanas Aydin, Erbil Cakar, Nazan Tarhan Usal, Ebru Cogendez, Enis Ozkaya, Cemile Bicer, Ozcan Erel

ABSTRACT Objective: To investigate the efficacy of first-trimester thiol/disulfide homeostasis (t/dh), a new oxidative stress marker, in predicting preeclampsia. Study Design: Prospective cohort study. Place and Duration of Study: Department of Obstetrics and Gynecology, University of Health Science...

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Risk Factors for Systemic Inflammatory Response Syndrome in Patients with Negative Preoperative Urine Culture after Percutaneous Nephrolithotomy

By Ekrem Akdeniz, Kemal Ozturk, Muhammet Bahaettin Ulu, Metin Gur, Suleyman Tumer Caliskan, Emine Sehmen

ABSTRACT Objective: To explore the risk factors for systemic inflammatory response syndrome (SIRS) after percutaneous nephrolithotomy (PCNL) in patients with preoperative negative urine culture (UC). Study Design: Observational study. Place and Duration of Study: Department of Urology, Gazi Hospital...

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Correlation between Circulating Tumor Cells and Plasma D-dimer and Clinicopathological Characteristics of Patients with Non-small Cell Lung Cancer

By Junfu Wang, Haibo Liu, Xiaoming Sun, Qiaoling Liu, Shuyi Han, Liangming Zhu

ABSTRACT Objective: To study the relationship between circulating tumor cells (CTCs) and plasma D-dimer (D-D) and their correlation with clinicopathological characteristics of patients with non-small cell lung cancer (NSCLC). Study Design: A descriptive study. Place and Duration of Study: Depar...

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The Prognostic Effects of Clinicopathological Features on Rectal Cancer Patients undergoing Neoadjuvant Chemoradiotherapy

By Alaettin Arslan, Ebru Akay, Gamze Turk, Saliha Karagoz Eren

ABSTRACT Objective: To investigate the effects of clinicopathological features on disease-free survival (DFS) and overall survival (OS) in in-patients with local advanced rectal cancer (LARC) who received neoadjuvant chemoradiotherapy (nCRT). Study Design: Observational study. Place and Duration of ...

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Comparison of the Recurrence Rate of Entropion via Subciliary Route and Transconjunctival Route in Combined Lateral Tarsal Strip with Retractor Advancement Procedure for Involutional Entropion Correction

By Faisal Aziz Khan, Mohammed Farooq Hyder, Shafaq Pervez Khan Niazi, Umair Tariq Mirza

ABSTRACT Objective: To compare the recurrence rate of entropion via subciliary route and transconjunctival route in combined lateral tarsal strip with retractor advancement procedure for involutional entropion correction. Study Design: Quasi-experimental study. Place and Duration of Study: Departme...

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Assessment of Refractive Outcomes of Femtosecond-assisted Laser in Situ Keratomileusis (LASIK) for Hyperopia

By Sadia Humayun, Mazhar Ishaq, Aisha Fawad, Syed Fawad Mashhadi, Quratulain Humayun, Sabahat Arzoo

ABSTRACT Objective: To determine the effect of refractive treatment in terms of safety, efficacy, stability, accuracy, and predictability with Wavefront Optimized Laser-assisted in situ keratomileusis (LASIK) on hyperopia. Study Design: Descriptive, analytical study. Place and Duration of Study: Ar...

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Minimally Invasive Parathyroidectomy: Are Auxiliary Methods Necessary?

By Hakan Bolukbasi, Serhan Yılmaz, Erkan Somuncu, Yasin Kara, Mehmet Abdussamet Bozkurt

ABSTRACT Objective: To determine the success rate of minimally invasive parathyroidectomies (MIPs) with preoperative scintigraphy and ultrasonography, and to assess whether these imaging modalities are sufficient. Study Design: Observational study. Place and Duration of Study:  Department...

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Cholecystectomy with Thoracic Epidural Anesthesia in Geriatric Patients

By Sedat Saylan, Ali Akdogan, Davut Dohman, Erdem Nail Duman

ABSTRACT Objective: To determine the outcome of thoracic epidural anaesthesia in open cholecystectomy procedures of comorbid advanced elderly patients. Study Design: Observational study. Place and Duration of Study: Faculty of Medicine, Karadeniz Technical University Hospital, Trabzon, Turkey during...

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Dermatoscopy and Reflective Confocal Microscopy for Facial Seborrheic Keratosis, Verruca Plana, and Nevus Pigmentosus

By Quansheng Lu, Shan Wang, Tong Wu, Guan Jiang

ABSTRACT Objective: To describe the features of facial seborrheic keratosis, verruca plana, and nevus pigmentosus by dermatoscopy and reflective confocal microscope (RCM). Study Design: Cross-sectional observational study. Place and Duration of Study: Dermatology Department of The Affiliated Hospita...

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Restenosis after Balloon Dilatation with versus without Stent Placement for Hepatic Vein Involvement Budd-Chiari Syndrome

By Xuedong Sun, Lulin Zhou, Maoqiang Wang

ABSTRACT Balloon angioplasty with or without stent placement has become the mainstream treatment of Budd–Chiari syndrome (BCS). Restenosis of hepatic vein (HV) is a tough problem. The aim of this study was to perform a meta-analysis to compare the restenosis in HV involvement type BCS patients...

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Strength of Motivation among Public and Private Dental Students for the Field of Education: A Comparative and Correlational Study

By Mian Saad Ahmed, Faisal Hassan, Shahab Ullah, Fazlina Shaid, Muhammad Sabih

ABSTRACT Objective: To compare and correlate the strength of motivation for the field of education among public and private dental students of Khyber Pakhtunkhwa. Study Design: Cross-sectional analytical study. Place and Duration of the Study: Khyber College of Dentistry (KCD), KMU Institute Dental...

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Embolisation of the Coronary Arterial Tree with Thick Contrast Material during Coronary Angiography

By Waleed M Ghaleb, Abdelfatah Elasfar, Mohsen Alarbash, Abdulrahman Aldiri, Abdulhalim Jamal Kinsara

ABSTRACT A 58-year male was referred to our centre with an acute inferior ST elevation myocardial infarction (STEMI). During the primary percutaneous coronary intervention, he suddenly collapsed with severe hypotension and severe bradycardia. The symptoms were attributed to an accidental embolisatio...

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First Fenestrated Endovascular Aortic Aneurysm Repair in Pakistan

By Usama Khalid Choudry, Omer Ehsan, Zahid Amin Khan, Amina Amin

Abstract Fenestrated grafts form an alternative to open surgery, and are already increasingly being offered as part of the standard spectrum of treatment in developed countries. The past two decades have seen rapid developments in fenestrated endovascular aneurysm repair (fEVAR)/branched (bEVAR) exp...

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Pancreatic Abscess Misdiagnosed and Treated as Pancreatic Cancer

By Deng-Yong Zhang, Zheng Lu

ABSTRACT A preoperative diagnosis of pancreatic cancer is not hundred percent accurate. Because of the uncertainty in the diagnosis of pancreatic tumours, some benign pancreatic diseases have been misdiagnosed as pancreatic cancer and treated with surgical resection. This approach has a significant...

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Peripheral Giant Cell Granuloma of Posterior Maxilla in a 9-Year Child

By Hamza Hassan Mirza, Abul Khair Zalan, Anser Maxood, Anika Gul, Zainab Memon, Muhammad Sulaiman

ABSTRACT Peripheral giant cell granuloma is a relatively uncommon benign reactive gingival lesion of the oral cavity. A 9-year boy presented with a painless, slow-growing, reddish-blue, soft tissue lesion on attached gingiva adjacent to maxillary right first and second premolars, which was interferi...

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Association between Intercanine Width and Mandibular Dental Arch Forms

By Saad Abdul Rehman, Sadia Rizwan, Syed Shah Faisal, Syed Sheeraz Hussain

ABSTRACT A descriptive cross-sectional study was conducted to investigate the association between intercanine width and the mandibular arch form in 109 dentate subjects, who visited Orthodontics Department from October 2018 to December 2019. Using Vernier caliper, the intercanine width was measured ...

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Safety and Efficacy of Aminophylline in Intrathecal Methotrexate-related Neurological Toxicity in Large Pediatric Oncology Centre

By Wajeeha Razi, Anwar Ul Haque, Hassaan Sadiq, Raza Ullah, Naeem Jabbar, Sadiq Mirza

ABSTRACT Children with acute lymphoblastic leukemia, receiving intrathecal methotrexate (IT-MTX), develop acute and subacute neurological dysfunction in 3-15% of cases. Altered level of consciousness, seizure, and stroke-like manifestations are among the most common presentations. MRI of the brain i...

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Polishing the Teaching of Affective Domain in Online Education

By Tayyeba Iftikhar Mirza, Usman Mahboob

ABSTRACT The COVID-19 pandemic has affected the overall education system in general and medical education in particular. While the cognitive and psychomotor domains were regularly taught in most medical schools, the affective domain was mostly left to informal teaching through role modelling. With t...

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Analysis of Door-to-Needle Time for Acute Stroke, and Factors Contributing for Delay in a County Hospital in Ireland

By Muhammad Mohsin Sajjad, John Corrigan

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Overfeeding: A Rare Cause of Failure to Wean Identified via Indirect Calorimetry

By Sanjith Saseedharan, Annapurna Chiluka

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Clinical Trials in Rehabilitation: The Dilemmas and Possible Solutions

By Arshad Nawaz Malik, Hina Tariq

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Targeted Drug Therapies for Bladder Microbiota: Myth or Future of Benign Prostatic Hyperplasia Treatment?

By Turgay Akgul

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Severe Hyponatremia following Cystoscopy and Urethral Dilation: An Unusual Late Complication

By Mir Ibrahim Sajid, Shanila Ahmed, Noman Ali

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Special Issue

Special Supplement 1 on COVID-19 | Volume 31 | Year 2021
Predictors of Mortality in Patients with COVID-19 Infection-associated Acute Kidney Injury

By Aysel Tocoglu, Hamad Dheir, Melike Bektas, Seyyid Bilal Acikgoz, Oguz Karabay, Savas Sipahi

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Has the COVID-19 Pandemic Increased Mortality Among Patients with Cancer Receiving Systemic Anticancer Treatments?

By Ayşe Demirci, Cemil Bilir, Emre Cakir, Burcu Gulbagci, Ilhan Hacibekiroglu, Ceyhun Varim

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Outcomes of Conservative Management of Acute Appendicitis during COVID-19 Pandemic

By Muzna Iftikhar, Sajida Shah, Inamullah Shah, Jamil Ahmad Shah, Mahvish Faisal

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Comparison of HRCT Chest and RT-PCR in Diagnosis of COVID-19

By Nadia Hanif, Ghazala Rubi, Nadia Irshad, Saima Ameer, Uzma Habib, Syed Razi Haider Zaidi

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The Effect of Tocilizumab on Inflammatory Markers in Survivors and Non-survivors of Severe COVID-19

By Said Amin, Fawad Rahim, Sher Bahadur, Mohammad Noor, Afsheen Mahmood, Huma Gul

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Clinical Characteristics and Outcomes among Patients with Covid-19 in Different Regions of the World

By Yuanlin Zhou, Huihai Fan

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Online Medical Education and Examinations during COVID-19: Perspectives of a Teaching Associate

By Syed Mujtaba Baqir, Fatima Mustansir

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Short-term Changes on Follow-up Chest X-rays of Familial Cluster of COVID-19 Cases

By Chun-Xue Wu, Dong-Dong Rong, Yan-Hong An, Yi Shan, Jie Lu

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Right to Left Intrapulmonary Shunt in a Case with COVID-19-associated Pneumonia

By Maimoona Siddique, Muhammad Khalid Nawaz, Muhammad Bin Khalid, Aitzaz Rai

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Recurrence of COVID-19 Documented with RT-PCR

By Rohat Ak, Erdal Yilmaz, Avni Uygar Seyhan, Fatih Doganay

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COVID-19 Presenting with Spontaneous Pneumothorax

By Intisar Ahmed, Hunaina Shahab, Muhammad Arslan Ahmed, Muhammad Sohaib

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Protective Modifications in Ophthalmology Practice during COVID-19 Pandemic: Challenges and Lessons Learned

By Mohammad Idris, Eemaz Nathaniel

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Airway Management for Emergent Surgeries during COVID-19 Pandemic

By Muhammad Zahoor, Ihtisham Ul Haq

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Health Systems Approach to Ensure Quality and Safety Amid COVID-19 Pandemic in Pakistan

By Nousheen Akber Pradhan, Anam Shahil Feroz, Syed Mairajuddin Shah

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Imaging Patterns of Encephalopathy in Patients with COVID-19

By Kumail Khandwala, Fatima Mubarak, Muhammad Nadeem Ahmad

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A Single-centre Study of COVID-19 Antibody

By Sidra Ghazanfer, Hasan Osman Mahmood

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Association of Blood Groups with the Severity and Outcome of COVID-19 Infection in Children

By Attia Bari, Aimen Ch, Sidra Hareem, Iqbal Bano, Junaid Rashid, Masood Sadiq

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Prospective Effects of Covid-19 on Children: Probable Complications and Interventions

By Naeem Aslam Chughtai

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New Insight for Kidney Biopsy Series in Cases with COVID-19-related Acute Kidney Injury

By İlker Kaya

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