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Volume 33, 12 Issues, 2023

Journal of College of Physicians and Surgeons Pakistan (JCPSP), is an open access, peer reviewed monthly biomedical journal of the country published regularly since 1991. College of Physicians and Surgeons Pakistan is the parent body of this Journal.

The College of Physicians and Surgeons of Pakistan (CPSP) is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide credits to educational activities.

CPSP designates '3 AMA PRA Category 1 Credits' for review of the manuscript of an original study.

Important Announcement for Authors

"A companion journal of JCPSP (the official journal of CPSP) has been launched by the name of JCPSP Case Reports. Submission of Case Reports is now open."
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Latest Articles
Volume 33 | Issue 3 | March 2023
Need of Countrywide Genetic Risk Scores (GRS) or Polygenic Scores (PGS) for Type-2 Diabetes Mellitus

By Sikandar Hayat Khan

Association Between Gastric Antral Cross-sectional Area and Postoperative Nausea and Vomiting in Patients Undergoing Laparoscopic Cholecystectomy

By Kai Wang, Junyu Tao, Zhangrui Hu, Zixuan Guo, Jing Li, Wenjun Guo

ABSTRACT Objective: To explore the predictive value of gastric antral cross-sectional area (CSA) in the occurrence of postoperative nausea and vomiting (PONV) by analysing the association between gastric antral CSA measured by ultrasound and frequency of PONV after laparoscopic cholecystectomy. Stud...

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Highly Sensitive and Ultrafast Liquid Chromatography-tandem Mass Spectrometry Internal Standard Method for Determination of Alpha-Tocopherol in Serum and Application of Validated Method on Patient Serum Samples in Pakistan

By Humera Shafi Makhdoom, Mohammad Dilawar Khan, Omar Rasheed Chughtai, Zeerak Abbas, Areeba Azad, Hijab Batool

ABSTRACT Objective: To optimize and validate a specific, sensitive and fast liquid Chromatography coupled to triple quadrupole Mass Spectrometric (LC-MS / MS) technique for accurate detection of serum α-tocopherol (Vitamin E) levels. Study Design: An experimental based study. Place and Duratio...

A Statistical Model for Early Recognition of Patients Requiring Transfer to Palliative Care (ERPAC)

By Cihangir Dogu, Ayse Muge Karcioglu, Isil Ozkocak Turan, Handan Ankarali

ABSTRACT Objective: To develop a scoring system to identify patients at an early stage who will need palliative care during intensive care follow-up. Study Design: Analytical study. Place and Duration of Study: Ankara City Hospital, Neurology and Orthopaedics Hospital, General Intensive Care Unit, A...

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Risk of Cardiovascular Death in Osteosarcoma

By Yukun Jia, Yu Xiong, Zhan Peng, Guangye Wang

ABSTRACT Objective: To assess the risk of cardiovascular mortality (CVM) in patients with osteosarcoma. Study Design: Descriptive study. Place and Duration of the Study: Department of Orthopaedics, The People’s Hospital of Baoan, Shenzhen, Guangdong, China, from 1st January 2019 to 1st Ja...

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Concordance of Chromosomal Microarray Analysis in Prenatal Diagnosis of Fetuses with Abnormal Ultrasonographic Soft Markers

By Yan Lu, Caihong Liu, Yan Ji

ABSTRACT Objective: To analyse the effect of chromosomal microarray analysis (CMA) in the prenatal diagnosis of fetuses with abnormal ultrasonographic soft markers. Study Design: Descriptive study. Place and Duration of the Study: Prenatal Diagnostic Centre, Huizhou Central People’s Hospital,...

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Fournier's Gangrene: Evaluation of Patient Outcomes Using Clinical Data and Prognostic Biomarkers

By Burak Ucaner, Sacit Altug Kesikli, Mehmet Zeki Buldanli, Mehmet sabri Ciftci, Oguz Hancerliogullari

ABSTRACT Objective: To find out the outcomes of Fournier’s gangrene (FG) patients using clinical data and prognostic biomarkers based on the current literature. Study Design: Descriptive study. Place and Duration of the Study: Department of General Surgery, University of Health Sciences, Gulha...

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Different Translocations of Multiple Myeloma on Fluorescent In Situ Hybridization (FISH) with Clinical Correlation

By Muhammad Umar, Hamid Saeed Malik, Baber Zaman, Muhammad Waleed Ahmad, Fauzia Khan, Hira Nadeem

ABSTRACT Objective: To evaluate the association of chromosomal translocations in multiple myeloma (MM) detected by Fluorescent In Situ Hybridization (FISH) and its clinical characteristics. Study Design: Cross-sectional study. Place and Duration of the Study: Department of Haematology, Armed Forces...

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Expression of TLE-1 in Gastrointestinal Stromal Tumour and Its Relationship to Clinicopathological Parameters

By Bermal Hasbay, Fazilet KayaselCuk

ABSTRACT Objective: To determine the significance of the TLE-1 expression in GISTs, and evaluate the predictive value of TLE-1 expression in patient survival. Study Design: An observational study. Place and Duration of the Study: The archives Department of Pathology, Başkent University, Adana, Turk...

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Development and Validation of In-house HEp-2 Cell Slides for Detection of Antinuclear Antibodies (ANA) by Indirect Immunofluorescence

By Muhammad Zain Arshad, Dawood Ahmad, Muhammad Hussain, Hamid Nawaz Tipu, Muhammad Omair Riaz, Ayesha Tanveer

ABSTRACT Objective: To develop and validate in-house HEp-2 cell slides for the detection of ANA by indirect immunofluorescence. Study Design: Cross sectional validation study. Place and Duration of the Study: Department of Immunology, Armed Forces Institute of Pathology Rawalpindi, Punjab, Pakistan,...

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Clinical and Biochemical Characteristics of COVID-19 Patients During the Delta-Omicron Wave with Risk Assessment of Adverse Outcomes

By Sahar Iqbal, Saeed Khan, Muhammad Asif Qureshi, Muneeba Ahsan Sayeed, Bilal Ahmed Khan, Sidra Zaheer, Hafsa Faruqui, Abdul Wahid Rajput

ABSTRACT Objective: To compare clinical and biochemical characteristics of hospitalised COVID-19 patients and risk assessment of disease outcomes Study Design: Descriptive study. Place and Duration of the Study: Department of Pathology, Dow International Medical College and Sindh Infectious Diseases...

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Frequency and Antibiotics Sensitivity Pattern of Culture-Positive Salmonella Typhi in Children

By Mubashir Ahmad, Nownhall Shah, Muhammad Asif Siddiqui

ABSTRACT Objective: To calculate the frequency of positive blood culture in clinically diagnosed cases of enteric fever and antibiotic sensitivity patterns in culture-positive cases of S.typhi Study Design: Observational Study. Place and Duration of the Study: Department of Paediatrics Medicine, Ser...

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Comparison of the Impact of SGLT2-Inhibitors and Exenatide on Body Fat Composition

By Esma Agcakaya, Hacer Hicran Mutlu, Ayse Erbakan, Mehmet Sargin

ABSTRACT Objective: To investigate the effect of SGLT2-i and GLP-1RA as an add-on therapy to metformin on weight loss and body composition, and to compare their effects on glucose and lipid parameters. Study Design: A descriptive study. Place and Duration of the Study: Goztepe Prof Dr Suleyman ...

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Trajectory of Anxiety, Depression and Quality of Life in Ankylosing Spondylitis: A Descriptive Study

By Bilinc Dogruoz Karatekin, Afitap Icagasioglu, Fusun Moral Oguz, Seyma Nur Bayindir, Ozge Pasin

ABSTRACT Objective: To investigate anxiety, depression, and health-related quality of life (HRQoL) over 15 years and associations between demographic, disease-related variables, anxiety and depression, and HRQoL in patients with AS. Study Design: Descriptive study. Place and Duration of the Study: I...

Protective Effects of N-Acetyl Cysteine on Undescended Testis after Orchiopexy: A Rat-model Study

By Eray Kemahli, Ugur Uyeturk, Ayhan Cetinkaya, Sevilay Erimsah, Ummugul Uyeturk, Adnan Gucuk

ABSTRACT       Objective: To assess the effectiveness of utilising N-acetyl cysteine (NAC) to treat tissue damage brought on by undescended testis (UT) in rats after orchiopexy. Study Design: Experimental study. Place and Duration of the Study: Bolu Abant İzzet Baysal...

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Substance Abuse and Mental Health Issues Among HIV/AIDS Patients

By Khunsa Junaid, Saira Afzal, Muhammad Daood, Meha Siddiqui

ABSTRACT Psychiatric morbidity commonly coexists with substance abuse and HIV/AIDS around the globe. This review study aimed to determine the available literature on the prevalence of common substance abuse/use and common mental health illnesses among HIV/AIDS patients worldwide to help policymakers...

Clinicopathological Factors Affecting Mucin 1, Mucin 2, and Mucin 5AC Staining in Patients who Underwent Resection for Colorectal Cancer

By Turgut Anuk, Hatice Beseren, Yalcin Polat, Ozkan Ozden, Tolga Kalayci

ABSTRACT Objective: To investigate the clinicopathological factors affecting mucins (MUC 1, MUC 2, and MUC 5AC) staining in patients who underwent resection for colorectal cancer. Study Design: An observational study. Place and Duration of the Study: Department of General Surgery and Department of P...

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Haematopoietic Stem Cell Transplantation (HSCT) for Primary Immune System Disorders in Children: A Single Centre Experience

By Asghar Ali Kerio, Tariq Azam Khattak, Tariq Ghafoor, Muhammad Yousaf, Nighat Shahbaz
, Qamar Un Nisa Chaudary

ABSTRACT Objective: To determine the outcomes of allogeneic HSCT in children with primary immune system disorders (PID). Study Design: Descriptive Cross-sectional study. Place and Duration of the Study: Armed Forces bone marrow transplant centre / National Institute of Bone Marrow Transplant (AFBMTC...

Comparison of the Conventional PNL with Ecirs in the Treatment of Complete Staghorn Kidney Stones

By Hasan Nedim Goksel Goktug, Ufuk Ozturk, Sertac Cimen, Serafettin Kaymak, Ahmet Emin Dogan, Muhammet Abdurrahim Imamoglu

ABSTRACT Objective: To analyse the results of conventional percutaneous nephrolithotomy (PNL) and endoscopic combined intrarenal surgery (ECIRS) in treating complete staghorn kidney calculi. Study Design: A comparative study. Place and Duration of the Study: Department of Urology, Uni...

Relationship between Migraine and Patent Foramen Ovale Observed by Contrast-enhanced Transthoracic Echocardiography

By Xuerong Fu, Mingxing Li

ABSTRACT To observe the association between migraine and patent foramen ovale (PFO) using contrast-enhanced transthoracic echocardiography (cTTE). Eighty-five migraine with aura (MA) patients and 85 migraine without aura (MO) patients from January 2020 to February 2022 were divided into group A and ...

The Effect of Ligamentotaxis on Clinical and Radiological Outcomes in Thoracolumbar Burst Fractures with High McCormack Grade

By Mehmet Secer, Hande Gurbuz, Anil Gulcu

ABSTRACT The aim of this study was to investigate the effect of ligamentotaxis performed in combination with the posterior surgical approach in thoracic and lumbar burst fractures due to high-energy trauma with high McCormack scores (≥7). This observational study was conducted at the University ...

Rationale of Establishment of Cardio-oncology Multi-
disciplinary Team Tumour Boards in Pakistan

By Ahmed Nadeem Abbasi, Calogero Casa, Andrea Daviero

Origin of Kehr Sign in
Traumatic Splenic Trauma

By Steven Howard Yale, Halil Tekiner, Eileen Scott Yale

Emotional Intelligence Training can be Incorporated as an Essential Component of Postgraduate Medical Education: Paving the Way Towards the Development of Multidisciplinary Team Culture

By Ahmed Nadeem Abbasi, Maria Tariq, Muneeb Uddin Karim, Calogero Casa

Importance of Development of Rare Cancers National Tumour Board

By Laraib Khan, Ahmed Nadeem Abbasi, Sohail Rasool

Superselective Renal Artery Embolization for Serious Renal Hemorrhage after Percutaneous Renal Biopsy in a Young Male

By Xiaodong Li, Bingmu Liu, Yancong Guo