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Volume 33, 12 Issues, 2023

Journal of College of Physicians and Surgeons Pakistan (JCPSP), is an open access, peer reviewed monthly biomedical journal of the country published regularly since 1991. College of Physicians and Surgeons Pakistan is the parent body of this Journal.

The College of Physicians and Surgeons of Pakistan (CPSP) is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide credits to educational activities.

CPSP designates '3 AMA PRA Category 1 Credits' for review of the manuscript of an original study.

Important Announcement for Authors

"A companion journal of JCPSP (the official journal of CPSP) has been launched by the name of JCPSP Case Reports. Submission of Case Reports is now open."
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Latest Articles
Volume 33 | Issue 5 | May 2023
Cancer Registry – What is the Need to be Attentive and Why Now?

By Ambreen Arif, Huma Qureshi

Comparison of the Analgesic Efficacy of Lidocaine Spray versus Tramadol and Fentanyl for Pain Control in Rib Fractures

By Ahmet Burak Erdem, Safa Donmez, Alp Sener

ABSTRACT Objective: To compare the analgesic efficacy of lidocaine spray with tramadol hydrochloride and fentanyl citrate in rib fractures. Study Design: A randomised, controlled open-label study. Place and Duration of the Study: Ministry of Health Ankara City Hospital, Turkiye, from June to Novembe...

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Cardiac Troponin-I, A Biomarker for Predicting COVID-Induced Myocardial Damage Prognosis

By Abdul Rehman, Shagufta Yousuf, Ghulam Rasool Maken, Syed Rehan Asghar Naqvi, Ghulam Murtaza, Abeera Ahmad

ABSTRACT Objective: To analyse the utility of cardiac Troponin-I as a prognostic marker in COVID-19-induced myocardial injury. Study Design: A descriptive study. Place and Duration of the Study: COVID Intensive Therapeutic Unit (ITC) and Pathology Department, Combined Military Hospital (CMH), Malir,...

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Assessment of Dry Socket after Mandibular Third Molar Surgery Using Platelet-Rich Fibrin - A Prospective Clinical Study

By Nosheen Iqbal, Muhammad Usman Khalid, Omer Sefvan Janjua, Khurram Jah Zafar, Malik Muhammad Usama

ABSTRACT Objective: To determine the efficacy of Platelet-Rich Fibrin (PRF) in preventing Dry Socket (DS) after mandibular third molar surgery in comparison with the control group. Study Design: Experimental study. Place and Duration of the Study: Oral and Maxillofacial Surgery Department, Dent...

Condylar Size and Position, Comparison among Different Sagittal Skeletal Relationships: A CBCT Study

By Qurat ul Ain Tariq, Abdullah Jan

ABSTRACT Objective: To compare the size and spatial position of mandibular condyles among different sagittal skeletal patterns using CBCT imaging. Study Design: A cross-sectional study. Place and Duration of the Study: Department of Orthodontics, Armed Forces Institute of Dentistry, Rawalpindi, Paki...

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Comparative Effects of Azithromycin and Probiotics for Treatment of Acne Vulgaris

By Mushayada Irshad, Akbar Waheed Syed, Muhammad Waseem Shahid, Uzma Naeem, Mehreen Mirza, Samarah Naeem

ABSTRACT Objectives: To measure the efficacy of oral probiotics when combined with a topical agent, and to compare the efficacy of Azithromycin, Probiotics, and their combination for the treatment of acne vulgaris. Study Design: A quasi-experimental study. Place and Duration of the Study: Pharmacolo...

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Quality of Life Index in Patients with Vitiligo

By Saadia Tabassum, Atiya Rahman, Rabia Ghafoor, Qamaruddin Khan, Najia Ahmed, Tazein Amber, Nadia Iftikhar, Bazil Musharraf, Nadia Ali Azfar, Uzma Bashir, Zartash Arshad, Safia Awan

ABSTRACT Objective: To ascertain the quality of life (QoL) impairment among the Pakistani population with vitiligo and to determine the relationship between sociodemographic and clinical characteristics. Study Design: Cross-sectional study. Place and Duration of the Study: Dermatology Outpatien...

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Association of Vitamin D with Moderate to Severe Acne Vulgaris

By Tayyaba Iqbal, Sadaf Ahmed Asim, Sadia Bhatti, Madiha Sajid, Reema Mirza, Zille Huma

ABSTRACT Objective: To determine the association of vitamin D deficiency in moderate to severe acne. Study Design: A comparative study. Place and Duration of the Study: Dermatology OPD at Dow University of Health Sciences, Karachi, Pakistan, from December 2021 to May 2022. Methodology: Fifty patient...

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Association of Polycystic Ovarian Syndrome with Endometrial Carcinoma among Premenopausal Females

By Khansaw Iqbal, Zohra Khanum, Asia Parveen

ABSTRACT Objective: To determine the association of polycystic ovarian syndrome (PCOS) with endometrial carcinoma in premenopausal females. Study Design: Cohort study. Place and Duration of the Study: Department of Obstetrics and Gynaecology, Unit II, Sir Ganga Ram Hospital, Lahore, Paki...

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Acute Kidney Injury Due to Obstetric Complications

By Pooran Mal, Muhammad Nadeem Ahsan, Mukesh Kumar, Sunil Gurbukshani, Aqsa Fatima, Iqra Khanzada

ABSTRACT Objective: To evaluate the factors, causes, and outcomes of acute kidney injury (AKI) among pregnant females admitted to a tertiary care hospital. Study Design: An observational study. Place and Duration of the Study: Department of Nephrology, Liaquat University Hospital, Hyderabad, from Ap...

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Utility of Different Scoring Systems for the Diagnosis of Thrombotic Microangiopathies

By Seda Yilmaz, Ozcan Cenelİ, Atakan Tekinalp

ABSTRACT Objective: To investigate the appropriateness of Bentley and plasmic scores and ADAMTS-13 activity to distinguish between primary thrombotic microangiopathies (TMA) syndromes and other thrombotic microangiopathies, as well as primary thrombotic microangiopathies (TTP, complement-relate...

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Ki-67 Quantification in Breast Cancer by Digital Imaging AI Software and its Concordance with Manual Method

By Talat Zehra, Mahin Shams, Zubair Ahmad, Qurratulain Chundriger, Arsalan Ahmed, Nazish Jaffar

ABSTRACT Objective: To validate the concordance of automated detection of Ki67 in digital images of breast cancer with the manual eyeball / hotspot method. Study Design: Descriptive study. Place and Duration of the Study: Jinnah Sindh Medical University, Karachi, from 1st January to 15th February 2...

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A New Mortality Prediction Model in Advanced Stage Cancer Patients Requiring Hospitalisation while Receiving Active Systemic Therapy

By Kubilay Karaboyun, Yakup Iriagac, Eyyup Cavdar, Okan Avci, Erdogan Selcuk Seber

ABSTRACT Objective: To predict short and long-term mortality in patients who were admitted to the emergency department and then hospitalised unplanned in medical oncology-ward. Study Design: An observational study. Place and Duration of the Study: Department of Medical Oncology, Tekirdag Namik&...

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Comparative Effects of Focused and Radial Extracorporeal Shock Wave Therapies on Lateral Epicondylitis: A Randomised Sham-controlled Trial

By Seyhmus Kaplan, Volkan Sah, Sezai Ozkan, Cihan Adanas, Veysel Delen

ABSTRACT Objective: To evaluate and compare the effects of radial and focused types of extracorporeal shock wave therapy (ESWT) on lateral epicondylitis. Study Design: A randomised sham-controlled trial. Place and Duration of the Study: Department of Sports Medicine, Yuzuncu Yil University Hospital,...

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Karachi Cancer Registry (KCR): Consolidated Data of 5-years 2017-2021

By Shahid Pervez, Adnan A. Jabbar, Ghulam Haider, Muhammad A. Qureshi, Shamvil Ashraf, Fouzia Lateef, Muhammad Khurshid, Imtiaz Bashir, Manzoor Zaidi, Naureen Mushtaq, Zehra Fadoo, Mohammed S. Quraishy, Nausheen Yaqoob, Ejaz Alam, Huma Qureshi

ABSTRACT Objective: To collect and analyse epidemiologic data of all malignancies by age group and gender for the Karachi population to estimate the cancer incidence of 5-years (2017-2021) and identify major risk factors for setting priorities towards cancer control programs. Study Design: Obse...

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rs719725 Polymorphism and Colorectal Cancer Susceptibility: A Meta-analysis

By Xin Zhou, Aijun Chen, Tingting Zhang

ABSTRACT Many studies have suggested an association between 9p24 rs719725 polymorphism and colorectal cancer (CRC) risk, but with inconsistent results. This meta-analysis aimed to summarise the overall association of rs719725 polymorphism with CRC risk. Nine eligible articles with 21 case-control st...

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Effectiveness of Evidence Based Physical Therapy Management Approaches in Sacroiliac Joint Dysfunction: A Meta-analysis

By Sabrina Sabrina, Sumaira Farooqui, Muhammad Abid Khan, Amna Aamir Khan, Faisal Ali Khan

ABSTRACT Worldwide the prevalence of sacroiliac joint dysfunction (SIJD) lies within a range of 13% to 30%. In approximately 10% to 25% of patients, SIJD is a cause of mechanical low back and leg pain. A total of 498 subjects included in 10 studies conducted from 2018 to 2022 were included in this ...

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A Cholangiocarcinoma Prediction Model Based on Random Forest and Artificial Neural Network Algorithm

By Jianhua Liao, Chunyan Meng, Baoqing Liu, Mengxia Zheng, Jun Qin

ABSTRACT Objective: To construct a prognostic model using artificial neural network (ANN) approach, providing an idea for the prediction and diagnosis of cholangiocarcinoma (CCA). Study Design: Experimental study. Place and Duration of the Study: Department of General Surgery, Zhenjiang Hospital, Z...

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Urea Breath Testing to Detect Helicobacter pylori in Patients with Peptic Ulcer Bleeding During Proton Pump Inhibitor Treatment

By Zhipeng Huang, Donghong Wei

ABSTRACT This was a descriptive study carried out from January to December 2021, at Quanzhou First Hospital, an affiliated hospital of Fujian Medical University, to investigate the efficacy of the urea breath test in detecting Helicobacter pylori infection in patients with peptic ulcer bleeding affe...

Mandatory Influenza Immunisation for Healthcare Workers

By Munazza Saleem

ABSTRACT Healthcare workers (HCWs) are at increased risk of contracting and spreading influenza, especially in annual outbreaks. To achieve a high level of health, this matter can be potentially solved with the implementation of mandatory flu vaccination policies. Despite ample evidence of vaccine e...

Leukaemia Cutis

By Aamer Aleem, Farjah Algahtani

Avoiding “COVID Blindness”: Advocating Cognitive Bias Teaching in the Context of COVID-19

By Fenghua Qian, Meina Zheng, Jian Jiao

Effect of Interscalene Brachial Plexus Block on Intracranial Pressure: Are the Measures of Optic Nerve Sheath Diameter Standardised with B-Scan?

By Mario Graziano, Marco Gioia, Danilo Biondino

Why are the Therapeutic Drug Monitoring Results of Voriconazole Inconsistent with CYP2C19 Genetic Testing?

By Lingti Kong, Mengyuan Xie, Manxue Jiang, Yulin Zhu

Deliberate Ingestion of Aluminum Phosphide Tablets as a Treatment for Dyspepsia

By Muhammad Mohsin Sajjad, Hamid Shahzad, Amina Tariq