5-Year Impact Factor: 0.9
Volume 34, 12 Issues, 2024

Journal of College of Physicians and Surgeons Pakistan (JCPSP), is an open access, peer reviewed monthly biomedical journal of the country published regularly since 1991. College of Physicians and Surgeons Pakistan is the parent body of this Journal.


The College of Physicians and Surgeons of Pakistan (CPSP) is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide credits to educational activities.

CPSP designates '3 AMA PRA Category 1 Credits' for review of the manuscript of an original study.


Important Announcement for Authors

"A companion journal of JCPSP (the official journal of CPSP) has been launched by the name of JCPSP Case Reports. Submission of Case Reports is now open."
Please visit https://jcpspcr.pk/.

Latest Articles
Volume 34 | Issue 9 | September 2024
The Power of Patient-Reported Outcomes in Oncology Practice

By Waqas Ahmed Khan, Saad Salim Naviwala


Postoperative Outcomes of the Awake Colorectal Surgery with Neuraxial Anaesthesia

By Ayca Tuba Dumanli Ozcan, Serhat Ocakli, Ezgi Erkilic, Yasemin Yalniz, Sadettin Er, Cengiz Ceylan

ABSTRACT Objective: To determine the outcome of awake surgery with combined spinal epidural in geriatric colon cancer patients with advanced comorbidity. Study Design: Quasi-experimental study. Place and Duration of the Study: Department of Anaesthesiology and Reanimation, Ankara Bilkent City Hospit...

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Intrathecal Dexmedetomidine as an Adjuvant to Low Dose Hyperbaric 0.5% Bupivacaine on Haemodynamic Parameters in Patients Undergoing Transurethral Resection of Prostate

By Nida Shafqat, Syed Muhammad Abbas, Muhammad Qamar Abbas, Muhammad Faisal Farooq, Muhammad Siddique, Shakeel Malik

ABSTRACT Objective: To determine the role of dexmedetomidine in potentiating the local anaesthetic efficacy of a low dose of bupivacaine when used as an adjuvant. Study Design: A prospective, double-blind, randomised study. Place and Duration of the Study: Department of Anaesthesia, Sindh Institute ...

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Dexmedetomidine versus Ketofol for Moderate Sedation in Endoscopic Retrograde Cholangiopancreatography

By Nida Aqeel, Muhammad Qamar Abbas, Syed Muhammad Abbas, Muhammad Faisal Farooq, Muhammad Siddique, Shakeel Malik

ABSTRACT Objective: To compare the efficacy of dexmedetomidine versus ketofol for moderate sedation in patients undergoing endoscopic retrograde cholangiopancreatography (ERCP). Study Design: Randomised controlled trial. Place and Duration of the Study: Department of Anaesthesia, SICU and Pain Manag...

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Diagnostic Accuracy of Polymerase Chain Reaction Against Giemsa Staining on Tissue Biopsy for Cutaneous Leishmaniasis

By Aleena Khalid, Maria Mushtaq Gill, Irfan Ali Mirza, Sakeenah Hussain Naqvi, Syed Adeel Hussain Gardezi, Rabia Sajjad

ABSTRACT Objective: To evaluate the diagnostic accuracy of a commercial real-time polymerase chain reaction (PCR) kit targeting 18S rRNA against Giemsa-stained tissue slides in patients clinically suspected of cutaneous leishmaniasis (CL). Study Design: Cross-sectional analytical study. Place ...

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Effect of Gender on Metabolic and Neurodevelopmental Parameters of Postnatally Growth-Restricted Rats Undergoing Catch-Up Growth

By Faiza Ikram, Muhammad Ali Rabani, Sidra Arshad, Barkat Ullah Khan, Muhammad Usman Bashir

ABSTRACT Objective: To determine the long-term effects of early postnatal malnutrition and various degrees of catch-up growth on metabolic (serum glucose, leptin, triacylglycerides) and neurodevelopmental parameters (learning and memory) among male and female rodent models, mimicking human preterm i...

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Microplastic in Gastric Fasting Liquid and Associated Gastric Pathology

By Duygu Felek, Onur Ilkay Dincer, Erol Cakmak

ABSTRACT Objective: To determine the presence of microplastics in the stomach, and the relationship between pathological changes in stomach tissue and microplastics. Study Design: An analytical study. Place and Duration of the Study: Department of Internal Medicine, Sorgun State Hospital, Yozgat, Tu...

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Comparison of the Efficacy of Laser and Hybrid Seton Methods in the Treatment of Perianal Fistula

By Ali Kemal Taskin, Mustafa Akar, Bulent Ozcetin

ABSTRACT Objective: To compare the efficacy and postoperative complications of laser and hybrid seton methods in the treatment of perianal fistula (PF). Study Design: A descriptive cross-sectional study. Place and Duration of the Study: Department of General Surgery, University of Health Sciences, B...

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Transparent Cap-Assisted Blunt Endoscopic Dissection of Gastric Submucosal Tumours Smaller than 2cm

By Linyun Xue, Yaowu Cai, Junwei Xie, Pengxing Xue, Zhonghua Huang, Wei Chen

ABSTRACT Objective: To evaluate the safety and effectiveness of transparent cap-assisted blunt dissection (TCABD) in the endoscopic resection of gastric submucosal tumours (G-SMT) smaller than 2cm, as compared with conventional electronic knife dissection. Study Design: Randomised controlled analysi...

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Diagnostic Accuracy of Immunohistochemical Expression of p16, MDM2, and CDK4 in Well-Differentiated and De-Differentiated Liposarcoma in MDM2 Fluorescent in situ Hybridisation Confirmed Cases

By Aysha Aslam, Hafeez Ud Din, Abdul Qadir, Umair Aslam, Saba Humayoun, Wajahat Ahmed

ABSTRACT Objective: To establish the diagnostic utility of immunohistochemistry markers p16 along with MDM2 and CDK-4 in confirming the diagnosis of well-differentiated and de-differentiated liposarcoma while taking Fluorescent in situ Hybridisation (FISH) as a gold standard. Study Design: A cross-s...


Response to Single Agent Cyclosporin in Patients with Non-Severe Aplastic Anaemia

By Munazza Nabi Awan, Nighat Shahbaz, Irsa Hidayat, Asghar Ali Kerio, Hashim Khan, Awais Siddiq

ABSTRACT       Objective: To determine the effectiveness of cyclosporin A (CSA) monotherapy in treating patients with non-severe aplastic anaemia (NSAA). Study Design: A cross-sectional observational study. Place and Duration of the Study: Department of Clinical Haematology...

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Comparison Between Pregabalin and Sertraline for Treatment of Uraemic Pruritus in Patients on Maintenance Haemodialysis: A Single-Centric Study

By Asad Abbas, Abdul Rehman Arshad, Muhammad Iqbal

ABSTRACT Objective: To compare oral pregabalin with oral sertraline for treatment of uraemic pruritus. Study Design: Randomised controlled trial. Place and Duration of the Study: Department of Nephrology, Pak Emirates Military Hospital Rawalpindi, Pakistan, from October 2023 to January 2024. Methodo...


Comparative Analysis of Gene Expression Profiles in Ovarian Clear Cell Carcinoma and High-Grade Serous Ovarian Cancer

By Chen Ye, Gang Hu, Xiaoni Zhou, Wen Deng, Kai Hu, Minglei Fu

ABSTRACT Objective: To evaluate disparities in gene expression profiles between Ovarian Clear Cell Carcinoma (OCCC) and High-Grade Serous Ovarian Carcinoma (HGSOC). Study Design: A descriptive study. Place and Duration of the Study: The Second People's Hospital of Jingdezhen, Jiangxi, China, be...

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The Maximum Threshold Value for HbA1c in Diabetic Patients Undergoing Elective Total Knee Arthroplasty

By Dahui Shen, Shoukang Sun, Zhifang Mu, Dong Yuefu

ABSTRACT Objective: To establish an optimal preoperative HbA1c threshold that enhances surgical outcomes and minimises postoperative complications in diabetic patients undergoing elective total knee arthroplasty (TKA). Study Design: Prospective cohort study. Place and Duration of the Study: Departme...

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Early Detection of Vascular Obstruction in Microvascular Flaps using Thermographic Camera

By Bilal Umar, Hafiz Khalil Ahmad, Barira Bashir, Ammara Rabbani, Muhammad Tariq Iqbal, Kamran Khalid

ABSTRACT Objective: To evaluate the early detection of vascular obstruction in microvascular flaps using a thermographic camera. Study Design: A cross-sectional study. Place and Duration of the Study: Department of Plastic Surgery, Jinnah Burn and Reconstructive Surgery Centre, Lahore, Pakistan, fro...

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Spontaneous Closure of Bile Leak in Abdominal Drain after Cholecystectomy: A Systematic Review

By Muhammad Tahir Ghani, Hafiz Muhammad Ijaz Ul Haq, Ibad Ur Rehman, Nain Sukh

ABSTRACT Bile leakage in abdominal drain after cholecystectomy is reported to close spontaneously without any intervention. The aim of this systematic review was to find out the amount and source of bile leaks that can be closed spontaneously and various factors associated with this closure. A syst...

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Inclisiran Treatment for Cardiovascular Disease Risk Reduction: A Systematic Review and Meta-Analysis

By Ya-Fang Chen, Si Li, Mei-Juan Wang, Meng-Yuan Wu, Zi-Chen Du, Li-Ping Wei

ABSTRACT This study was a meta-analysis of patient data to investigate the therapeutic effects of inclisiran on LDL-C, PCSK9, and TC in patients with atherosclerosis. Authors searched the Cochrane Library, Pubmed, EMBASE, and Web of Science databases for randomised controlled trials. Data of 4,731 s...

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Impact of Teaching Methods on Clinical Reasoning in Forensic Medicine: A Quasi-Experimental Study

By Mehreen Fatima, Arshad Khan, Ramlah Naz, Muhammad Yahya Noori

ABSTRACT Objective: To compare the effectiveness of flipped classroom and video-assisted learning techniques with didactic lectures in promoting clinical reasoning skills in Forensic Medicine. Study Design: Quasi-experimental study. Place and Duration of the Study: Department of Forensic Medicine, D...


Diagnostic Value of Pericholedochal Hypointense Ring Sign in MRI T2W Images in Cases of Pancreatic Ductal Adenocarcinoma

By Ozlem Akinci, Ercan Inci, Mustafa Orhan Nalbant, Ozkan Oner, Elif Hocaoglu

ABSTRACT Objective: To determine the value of hypointense pericholedocal ring sign in magnetic resonance imaging (MRI) T2W sequence images in the diagnosis of pancreatic ductal adenocarcinoma (PDA). Study Design: Retrospective observational study. Place and Duration of the Study: Department of Radio...


Frequency of Phenotypes and their Clinical and Hormonal Characteristics of Polycystic Ovarian Syndrome

By Rehana Rahim, Heera Urooj, Hina Gul

ABSTRACT Objective: To determine the frequency of phenotypes of polycystic ovarian syndrome (PCOS) in patients presenting with sub-fertility, and to compare the clinical and hormonal characteristics among them. Study Design: Descriptive cross-sectional study. Place and Duration of the Study: Depart...


Impact of Microsurgery and Postoperative Radiotherapy on Neurological Function in Intramedullary Spinal Cord Gliomas

By Xin Li, Zhen-Jie Liu, Liang Liang, Hai-Qing Dong, Xingang Zhao

ABSTRACT Objective: To assess the clinical efficacy of combined microsurgery and postoperative radiotherapy for the treatment of intramedullary spinal gliomas and its impact on neurological function. Study Design: An observational study. Place and Duration of the Study: Department of Neurosurgery, B...

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Metabolomics in Pakistan: A Comprehensive Analysis of Availability, Practices, and Challenges in Clinical Laboratories

By Hafsa Majid, Aamir Ijaz, Lena Jafri, Imran Siddiqui, Sibtain Ahmed, Aysha Habib Khan

ABSTRACT Objective: To comprehensively analyse the current state of metabolomics in clinical laboratories across Pakistan. Study Design: Cross-sectional survey. Place and Duration of the Study: Section of Chemical Pathology, Department of Pathology and Laboratory Medicine, The Aga Khan University, K...


Fenestrated and Branched Endovascular Aortic Aneurysm Repair for Treating Juxtarenal Aneurysms: An Update

By Zia Ur Rehman

ABSTRACT Fenestrated and branched endovascular aortic aneurysm repair (f-EVAR, b-EVAR, respectively) are technically challenging procedures that have evolved over the last decade for complex aortic aneurysms. They are alternatives to surgical repair for suprarenal and juxtarenal aortic aneurysms. A...


Pulmonary Embolism Risk Assessment in Acute Isolated Distal Deep Venous Thrombosis

By Jingqiu Zhang, Jin Wang, Yongping Lu

ABSTRACT The clinical risk factors and risk of developing pulmonary embolism (PE) in patients with acute isolated distal deep venous thrombosis (IDDVT) were assessed using single complete-duplex ultrasound (CDUS) imaging to reduce over-testing and over-treatment. This observational study was conduct...


Level and Influencing Factors of Clinical Nurses' Caring Behaviour in Southern China

By Mengna Liang, Qian Chen, Jiefang Xu, Qiaocong Lu

ABSTRACT A cross-sectional descriptive study was conducted to assess the level of caring behaviour among clinical nurses in Southern China and explore its influencing factors. The study was carried out in the Sixth Affiliated Hospital, South China University of Technology, Guangdong, China, from Dec...


Comment on: Effect of Pap Smear Cytology, HPV Genotyping On the Concordance of Colposcopy and Conization Results

By Hassam Nasir Khan Alizai, Aainah Pasha


COVID-19 Vaccination, Pregnant Woman, and Adverse Effects: Comment

By Rujittika Mungmunpuntipantip, Viroj Wiwanitkit


Well-Differentiated Neuroendocrine of Left Kidney

By Asif Husain Osmani, Anis Hussain Jaffery


Waardenburg Syndrome: A Rare Disorder with an Uncommon Manifestation in a Neonate

By Arshad Khushdil, Umair Anees, Moeez Hussain


Unchecked Antibiotic Access: A Looming Crisis in Pakistan

By Amna Khan, Sundus Dadan


Navigating the Vast Landscape of Academic Research Databases: A Guide for Researchers

By Muhammad Farooq, Hafsa Majid, Muhammad Umer Naeem Effendi