Journal of College of Physicians and Surgeons Pakistan (JCPSP), is the prestigious, peer reviewed monthly biomedical journal of the country published regularly since 1991. College of Physicians and Surgeons Pakistan is the parent body of this Journal.


The College of Physicians and Surgeons of Pakistan (CPSP) is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide credits to educational activities.

CPSP designates '3 AMA PRA Category 1 Credits' for review of the manuscript of an original study.


Latest Articles
Volume 29 | Issue 7 | July 2019
Evidence-based Medicine in Cardiac Imaging

By Maseeh uz Zaman, Nosheen Fatima

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Prenatal Ethanol-induced Effect on Cell Count of Pars Distalis of Pituitary Gland in the Rat Pups

By Nadia Rashid, M. Yunus Khan

Objective: To determine the effects of prenatal administration of ethanol on cell count in pars distalis of pituitary gland in the rat pups. Study Design: Experimental study. Place and Duration of Study: Department of Anatomy, College of Physicians and Surgeons Pakistan, Regional Centre, Islamab...

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Propofol Target-controlled Infusion in Anesthesia Induction during Painless Gastroscopy

By Dong-Ni Li, Guo-Qing Zhao, Zhen-Bo Su

Objective: To investigate the feasibility of using the eyelash reflex as an indicator to calculate the individualised optimal target concentration in anesthesia induction during painless gastroscopy. Study Design: Experimental study. Place and Duration of Study: China-Japan Union Hospital of Jili...

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Does MDR1 Analysis Predict Medical Therapy Modifications in Patients with Atrial Fibrillation?

By Ayhan Akoz, Kenan Ahmet Turkdogan, Bekir Dagli, Mucahit Kapci, Mucahit Avcil, Gokay Bozkurt, Ali Duman

Objective: To evaluate the effects of multi-drug resistance gene (MDR1) gene factor which is significant in medicinereceptor relationship, on readmission to the emergency department (ED) and medical therapy modifications in patients with atrial fibrillation (AF) readmitting to the emergency depart...

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Diagnostic Accuracy of Doppler Ultrasonography in Predicting Presence of Esophageal Varices in Patients with Hepatitis-C Induced Cirrhosis

By Ali Mansoor, Rabia Shaukat, Aamer Nadeem Chaudhary, Gohar Jehan

Objective: To determine the diagnostic accuracy of Doppler ultrasonography in predicting presence of esophageal varices in patients with hepatitis-C induced cirrhosis. Study Design: Descriptive analytical study. Place and Duration of Study: Department of Radiology, Jinnah Hospital, Lahore, from M...

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Clinical Biomarkers for Diagnosis of Damages in Individuals with Long-Term Exposure to X-Rays

By Khurram Rehman, Ghulam Mustafa, Muzammil Ahmad Khan, Zahid Rauf, Naqab Khan, Samiullah Khan

Objective: To determine altered manifestation of plasma proteins in X-rays technicians who are regularly exposed to low doses of radiations over a long period during their job. Study Design: Descriptive study. Place and Duration of Study: District Headquarters Hospital and Mufti Mahmood Memorial ...

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The Blunt Abdominal Trauma Bedside Ultrasonography Comparison with Trauma Severity Scores and Computerized Tomography

By Hizir Ufuk Akdemir, Fatih Caliskan, Celal Kati, Ahmet Baydin

Objective: To investigate the accuracy of focussed assessment sonography for trauma (FAST) bedside ultrasonography application in patients with blunt abdominal trauma and patient management, clinical outcome, and trauma severity scores. Study Design: Cross-sectional descriptive study. Place and D...

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Genetic Association of Apolipoprotein A5-1131T>C Polymorphism with Traits of Metabolic Syndrome

By Uzma Zafar, Saba Khaliq, Khalid Pervaiz Lone

Objective: To investigate the association of -1131T>C polymorphism of apolipoprotein A5 (APOA5) with metabolic syndrome and associated traits. Study Design: A cross-sectional comparative study. Place and Duration of Study: Department of Physiology, University of Health Sciences Lahore, from Ju...

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Comparison of the Efficacy of Nilotinib and Imatinib in the Treatment of Chronic Myeloid Leukemia

By Bang-Shuo Zhang, Yong-Ping Chen, Jing-Long LV, Yi Yang

Objective: To compare the efficacy of nilotinib and imatinib in the treatment of chronic myeloid leukemia (CML). Study Design: Analytical study. Place and Duration of Study: Department of Hematology, Chongqing Three Gorges Central Hospital, China, from January 2016 to January 2018. Methodology: ...

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Mahidol Scoring for Assessing Various Grades of β Thalassemia Intermedia

By Jovaria Mannan, Muhammad Naveed, Saher Gul Ahdi

Objective: To determine the effectiveness of Mahidol Scoring for assessing various grades of β thalassemia intermedia. Study Design: Cross-sectional study. Place and Duration of Study: Fatima Memorial Hospital, Shadman, Lahore, from August 2016 to August 2017. Methodology: A total of 150 pat...

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Effect of Pterygium Morphology on Recurrence with Preoperative Subconjunctival Injection of Mitomycin-C in Primary Pterygium Surgery

By Faisal Aziz Khan, Shafaq Pervez Khan Niazi

Objective: To investigate the effect of pterygium morphology on recurrence with preoperative subconjunctival injection of mitomycin-C in primary pterygium surgery. Study Design: Quasi-experimental study. Place and Duration of Study: Eye Department, Combined Military Hospital, Malir Cantt, Karachi...

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Comparison of Proximal Femoral Nail Antirotation and Dynamic Hip Screw Internal Fixation on Serum Markers in Elderly Patients with Intertrochanteric Fractures

By Bin Wang, Qingbai Liu, Yu Liu, Rui Jiang

Objective: To compare effect of proximal femoral nail antirotation (PFNA) and dynamic hip screw (DHS) internal fixation on serum inflammatory mediators (CRP, IL-1, IL-6 and TNF-α), myocardial injury markers (cTnT, CK-MB), and Myo-heart failure marker (BNP) in elderly patients with intertroch...

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Acute Necrotizing Encephalopathy

By Farida Jan, Sidra K. Jafri, Shahnaz H. Ibrahim

Objective: To describe the clinical profile of pediatric patients with acute necrotizing encephalopathy (ANE). Study Design: Case series. Place and Duration of Study: Aga Khan University Hospital, Karachi, Pakistan, from January 2014 to October 2017. Methodology: Retrospective review of medical r...

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Application of New Biomedical Materials in Orthodontic Appliances

By Hafiz Taha Mahmood, Adeel Tahir Kamal, Bushra Nazeer Khan, Mubassar Fida

This review article describes the application and characteristics of certain biomedical materials in orthodontic appliances. The elastic recoil of shape memory polymers, determination of the forces and moments experienced by the brackets and eventually by the tooth, reduction in treatment time by ...

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Cost Analysis of Emergency Department Visits by Geriatric Patients Living in Nursing Homes

By Murat Seyit, Atakan Yilmaz, Duygu Aras Seyit, Mert Ozen

Objective: To determine the cost analysis of emergency department (ED) visits by geriatric patients living in nursing homes. Study Design: Cross-sectional study. Methodology: Medical records of geriatric patients living in nursing homes who were admitted to the emergency department of the Hospit...

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Comparing Reinforcement Options for the Staple Line of Laparoscopic Sleeve Gastrectomy

By Mehmet Bayrak, Yasemin Altintas

Objective: To compare three reinforcement options (suture, fibrin glue, and no reinforcement) for staple line reinforcement of patients undergoing laparoscopic sleeve gastrectomy. Study Design: An experimental study. Place and Duration of Study: Ortadogu Hospital, Adana, Turkey, from 2013 to 2017...

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Predictors of Blood Culture Positivity in Pediatric Brucellosis

By Soner Sertan Kara, Yasemin Cayir

Objective: To investigate the predictors of blood culture positivity in children with brucellosis. Study Design: Descriptive study. Place and Duration of Study: Department of Pediatric Infectious Diseases in Erzurum Regional Training and Research Hospital, Turkey, from January to December 2015. ...

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SAPHO Syndrome in an Adult Male with Ulcerative Colitis

By Sana Sayeed, Areeba Imtiaz, Faiza Naz

Synovitis Acne Pustulosis Hyperostosis Osteitis (SAPHO) syndrome refers to a rare entity expressed by a combination of dermatological and osteoarticular manifestations. We report a case of this unique syndrome initially diagnosed as "Sweet's syndrome" due to more or less similar fea...

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Hirschsprung's Disease: A Rare Entity in Adults

By Tufail Ahmad, Misbah Riaz, Attaullah Khan, Mah Muneer Khan

Hirschsprung's disease (HD), a classic disease of childhood, may rarely escape diagnosis and lead to unique presentations in adults. By definition, the disease involves the rectosigmoid colon and is the result of a birth defect characterised by the absence of nerve cells responsible for the m...

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A Novel Mutation in the Choroideremia Gene in a Turkish Family

By Mustafa Iftikhar, Yulia Wolfson, Simrat Sodhi, Bushra Usmani, Hendrik P. N. Scholl, Syed M.A. Shah

Choroideremia is an X-linked recessive genetic disorder caused by mutations in the CHM gene. It is a rare retinal dystrophy that manifests as nyctalopia and vision loss, progressing to blindness in later stages. We report a 21-year Turkish man who presented with nyctalopia for the past 4-5 years. ...

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Haemangioendothelioma of Oral Cavity: A Rare Entity with Unusual Location

By Patel Nikita Rajendrakumar, Jagtap Kiran Suresh, Anjali Wadhwa, Pravin Mukhi, Pranjal Anil Patel

Hemangioendothelioma is a rare, locally aggressive vascular tumor, originating from soft tissue, bone, skin, and organs such as liver or lung and exceptionally the oral cavity. It is usually benign but can show variable grades of malignancy. Most of the cases of oral epithelioid hemangioendothelio...

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Effects of Somatostatin Combined with Pantoprazole on Serum C-Reactive Protein and Intercellular Adhesion Molecule-1 in Severe Acute Pancreatitis

By Jun Liu, Guoliang Wang, Yan Liu, Lei Huang, Xiangang Xu, Jun Wang

The objective of this study was to investigate effects of somatostatin combined with pantoprazole on serum C-reactive protein (CRP) and intercellular adhesion molecule-1 (ICAM-1) in severe acute pancreatitis (SAP) patients. It was an experimental study carried out from February 2016 to April 2018....

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Treating Foot Injuries by Grafting Pedicled Distal Peroneal Artery Perforator Flaps

By Changqing Hu, Yong Lian, Xiao Fan, Zhiping Sun

Treating mid- and forefoot wounds is challenging. We share our clinical experience and describe the treatment of foreand midfoot wounds by grafting pedicled distal peroneal artery perforator (PNAP) flaps. The study enrolled 21 patients with fore- and midfoot injuries, who underwent grafting with a...

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Analysis of CD 133 Expression in Oral Leukoplakia

By Anand Siddappa Tegginamani, Thomas George Kallarakkal, HS Vanishree, Khairiyah Binti Abd Muttalib

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Cirsoid Aneurysm of the Scalp: A Rare Finding in Neurosurgery

By Asra Ahmed, Rama Siddiqui, Abdul Ali Khan

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A Rare Non-obstetric Pathology in Pregnancy: Obstructive Sigmoid Colon Cancer

By Hasan Calis, Sidki Cetin

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Analysis of the Effect of Locking Compression Plate Internal Fixation for the Treatment of Limb Fractures

By Li Tan, Kai Yu, Jie Yang, Jian Yang, Dianying Zhang

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Special Issue

Special Supplement 1 | Volume 29 | June 2019
Case Reports – Special Supplement

By Editor JCPSP

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Growth Hormone and ACTH Deficiency in a Diabetic Adult

By Asif Ali Memon, Mehwish Gilani, Naveed Asif, Nida Basharat

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A Case of Dynamic Evolution of Thyrotoxicosis on Follow-up

By Cong Qing Miao, De Chuan Lu, Jing Jing Liu, Hui Xu, Xin Long Meng

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Coexistence of Papillary Thyroid Cancer and Primary Hyperparathyroidism: Report of Five Cases

By Hasan Calis, Nuraydin Ozlem, Serif Melih Karabeyoglu

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Primary Supraclavicular Cystic Lymphangioma in an Adult: A Rare Presentation

By Mansoor Tariq Azim, Syed Mukarram Hussain, Mohammad Awais Mughal

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An Adult Case of Thiamine-Sensitive Megaloblastic Anemia Syndrome Accidentally Diagnosed Myelodysplastic Syndrome

By Ali Kutlucan

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Endothelial Cysts of Adrenal Gland

By Zafar Ali, Hina Tariq, Usama Rehman

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JC Virus Infection: A Clinical Conundrum

By Hajra Farooq, Saifullah Khan Niazi, Misbah Noor, Eijaz Ghani

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Gastric Tuberculosis

By Naresh Kumar Seetlani, Khalid Imran, Qurat ul Ain Hafeez, Asif Ali, Pyar Ali Fazil, Bareeha Shaukat Sultan, Sulhera Khan

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Congenital Erythropoietic Porphyria: A Rare Case of Photosensitivity with Hemolytic Anaemia and Mental Retardation

By Nadia Shirazi, Payal Chauhan, Rashmi Jindal, Sohaib Ahmad

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Ischemic Skin Necrosis in Hepatorenal Syndrome Patient Secondary to Terlipressin

By Raheel Ahmed, Abdul Haseeb

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Adult-Onset Subacute Sclerosing Panencephalitis Presented with Neuropsychiatric Symptoms

By Abdulkerim Gokoglu, Hasan Tahsin Gozdas

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Primary Extra-renal Wilms' Tumor in Urinary Bladder: Rare Presentation of a Common Pediatric Malignancy

By Irfana Ishaq Sindhu, Haleema Saeed, Rabia Wali, Asma Mehreen

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Ocular Cicatricial Pemphigoid: Camouflaged as Persistent Conjunctivitis

By Jamal-uddin Mughal, Asif Jan Muhammad, Uzma Erum

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Traboulsi Syndrome in Pakistan

By Tehmina Awais, Mehmood Ali, Saad Alam Khan

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Shprintzen-Goldberg Syndrome: A Rare Disorder

By Attia Bari, Nadia Sadaqat, Nadia Nawaz, Iqbal Bano

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Primary Pulmonary Hypertension Associated with Asymptomatic Methylmalonic Aciduria in a Child

By Fatma Zohra Chioukh, Kamel Monastiri

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Primary Iliopsoas Abscess in a Neonate

By Muhammad Umar Nisar, Samer Sikander, Zenab Noorain, Mehr-un-Nisa Shahid Baig, Nadeem Akhtar

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A Rare Cause of Intractable Diarrhea of Infancy

By Salman Ali, Aroma Tariq, Maryam Ghuncha

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A Neonate with Upper GI Bleeding

By Suneeta Khemani, Huma Ghulam Qadir, Mumtaz Malik, Faiqa Hassan

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A Child with Weight Loss and Alacrimation: Triple A Syndrome

By Qurat ul Ain, Naveed Asif, Noreen Shahzad, Waqas Hanif Sheikh

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A Child with Ambiguous Genitalia: An Atypical Presentation

By Waqas Hanif Sheikh, Naveed Asif, Muhammad Younas, Nida Basharat, Qurat-ul-Ain , Noreen

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Erotomania in Depressive Psychosis: Mood Incongruent Delusion in a Depressive Young Woman

By Usama Bin Zubair, Sawera Mansoor

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Polyarthritis as the Initial Presentation of Hyper Eosinophilic Syndrome

By Lubna Nazir, Amir Riaz, Hamza Alam

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Bladder Hernia, Bladder Stone and Contralateral Bowel Hernia: An Usual Combination

By Akif Erbin, Halil Lutfi Canat, Burak Ucpinar, Hayati Malcik

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Adrenal Myelolipoma with Adrenocortical Adenoma Presenting with Hypertension Only

By Fan Yang, Chenyu Sun, Shiyu Pang, Juanjuan Cai, Hao Lin, Wanlong Tan

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Neoaorta Reconstruction Using Both Femoral Veins in a Patient with Secondary Aortoenteric Fistula

By Zia-ur Rehman

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Detection and Management of Pregnancy in Rudimentary Horn of Uterus

By Rizwana Parveen

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