Journal of College of Physicians and Surgeons Pakistan (JCPSP), is the prestigious, peer reviewed monthly biomedical journal of the country published regularly since 1991. College of Physicians and Surgeons Pakistan is the parent body of this Journal.


The College of Physicians and Surgeons of Pakistan (CPSP) is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide credits to educational activities.

CPSP designates '3 AMA PRA Category 1 Credits' for review of the manuscript of an original study.


Latest Articles
Volume 30 | Issue 6 | June 2020
A New FDA-approved Antibiotic for Drug-resistant Tuberculosis Treatment

By Faiza Ahmed, Kim Andrews, Dipali Arshad, Praneeth Nekuri

Download PDF Read Full Article


Levels of Ischemia: Modified Albumin in Patients Undergoing On-pump Coronary Artery Bypass

By Kadir Kaan Özsin, Abdullah Burak Balci, Umut Serhat Sanri, Orhan Guvenc, Senol Yavuz

ABSTRACT Objective: To investigate the effect of ischemia-modified albumin (IMA) during cardiopulmonary bypass (CPB). Study Design: Observational study. Place and Duration of Study: Department of Cardiovascular Surgery, Yuksek Ihtisas Training and Research Hospital, Bursa, Turkey, between January an...

Download PDF Read Full Article


Role of TLR4/NF-κB Signalling Pathway in Pulmonary Arterial Hypertension in Patients with Chronic Obstructive Pulmonary Disease

By Zhi Tong Zuo, Ya Ma, Yan Sun, Cui Qing Bai, Hai Yue Zhou, Bao Hua Chen

ABSTRACT Objective: To determine the role of toll-like receptor 4 (TLR4)/ nuclear factor kappa B (NF-κB) signalling pathway in pulmonary arterial hypertension (PAH) in patients with chronic obstructive pulmonary disease (COPD). Study Design: An experimental study. Place and Duration of Study: ...

Download PDF Read Full Article


Glutathione S-Transferase Theta 1 / Mu 1 Null Genotype and Risk of Development of Actinic Keratosis in Pakistani Population

By Muhammad Imran Bajwa, Amena Rahim, Muhammad Afzal, Amna Mahmood

ABSTRACT Objective: To assess the frequency and association of Glutathione S-Transferase Theta 1 and Glutathione S-Transferase Mu 1 null genotypes in development of actinic keratosis (AK) in a group of Pakistani population. Study Design: Case-control analytical study. Place and Duration of Study: De...

Download PDF Read Full Article


Efficacy of Low Dose Naltrexone in Psoriasis

By Sidra Khan, Rabia Ghafoor, Sana Kaleem

ABSTRACT Objective: To determine the efficacy of low dose naltrexone in the patients of psoriasis. Study Design: Non-randomised clinical trial. Place and Duration of Study: Department of Dermatology, Jinnah Postgraduate Medical Centre, Karachi from January to July 2019. Methodology: All patients of...

Download PDF Read Full Article


Scheuermann’s Disease as a Risk Factor for Lumbar Disc Herniation Recurrence

By Yan Ding, Shiqiao Lv, Guangrun Li, Shengjie Dong, Xuri Sun, Yunzhen Chen

ABSTRACT Objective: To verify whether Scheuermann’s disease (SD) is a risk factor for patients with recurrent lumbar disc herniation (rLDH) than in patients without recurrence. Study Design: Case-control study. Place and Duration of Study: Department of Orthopaedics, Yantaishan Hospital, China...

Download PDF Read Full Article


Prognostic Importance of Metastatic Site in Intermediate-risk Group Metastatic Renal Cell Cancer Treated with Tyrosine Kinase Inhibitors

By Cengiz Karacin, Irem Bilgetekin, Fatma Bugdayci Basal, Omur Berna Oksuzoglu

ABSTRACT Objective: To determine the prognostic importance of the metastatic site in metastatic renal cell cancer (mRCC) patients in the International Metastatic Renal Cell Carcinoma Database Consortium (IMDC) intermediate-risk. Study design: Observational study. Place and Duration of Study: Departm...

Download PDF Read Full Article


Comparison of Tumor Volume Dependent Mean Diameter with the Longest Diameter and Tumor Volume in Assessing Axillary Lymph Nodes in Breast Cancer

By Mehmet Kubat, Zülfikar Karabulut

ABSTRACT Objective: To investigate the effectiveness of tumor volume dependent mean diameter (Rmax) in determining axillary lymph node metastasis positivity instead of the largest diameter (Dmax) in breast cancer. Study Design: Descriptive study. Place and Duration of Study: Department of General ...

Download PDF Read Full Article


Correlation between Clinical Factors and Prognosis in Newly Diagnosed Multiple Myeloma

By Xiao-Qing Zhao, Shu-Ying Zhao, Wen-Xin Chen, Xiao-Wei Liu, Huai-Xiu Yan, Yong-Ji Lou

ABSTRACT Objective: To explore the correlation between clinical factors and the prognosis of multiple myeloma (MM). Study Design: A cohort study. Place and Duration of Study: At the Third Affiliated Hospital of Inner Mongolia Medical University, Mongolia from January 2014 to December 2018. Methodol...

Download PDF Read Full Article


Vascular Occlusion Role in the Etiopathohegenesis of Idiopathic Sudden Sensorineural Hearing Loss: Risk Analysis with Hematological Parameters

By Selcuk Yildiz, Sema Zer Toros

ABSTRACT Objective: To evaluate the concomittant metabolic disorders, mean platelet volume (MPV), and neutrophil to lymphocyte ratio (NLR) in patients with idiopathic sudden sensorineural hearingloss (SSNHL) in comparison to healthy controls. Study Design: Case-control study. Place and Duration of ...

Download PDF Read Full Article


Mortality Caused by Late-onset Sepsis in Very Low Birth Weight Infants: Risk Analysis and the Performance of Diagnostic Tools

By Hakan Ongun, Meltem Demir

ABSTRACT Objective: To assess the risk on late-onset sepsis attributed mortality in very low birth weight (VLBW) infants.    Study Design: Observational study. Place and Duration of Study: Level-III Neonatal Intensive Care Unit, İstinye University, Antalya Medical Park Hospital, Tur...

Download PDF Read Full Article


Diagnostic Value of Musculoskeletal Ultrasound in Rheumatoid Finger Arthritis

By Xiaofeng Wang, Guo Qian, Hongbo Duan

ABSTRACT Objective: To determine the value of musculoskeletal ultrasound (MSUS) in evaluating the pathological features and inflammatory lesions of rheumatoid finger arthritis. Study Design: A comparative study. Place and Duration of Study: Ningbo No. 6 Hospital, China, from September 2017 to Febru...

Download PDF Read Full Article


Correlation between Overactive Bladder Syndrome and Severity of Coronary Artery Disease in Postmenopausal Women

By Bahar Yuksel, Faruk Özgör, Murat Şahan, Semih Ozturk, Mehmet Mustafa Can, Omer Sarilar

ABSTRACT Objective: To analyse the correlation of overactive bladder (OAB) and severity of coronary artery disease (CAD) by using Gensini score in postmenopausal women. Study Design: Observational correlation study design. Place and Duration of Study: Haseki Training and Research Hospital, Istanbul...

Download PDF Read Full Article


Post-cardiac Surgery Chylopericardium

By Shi-Min Yuan

ABSTRACT Post-cardiac surgery chylopericardium is a rare complication. This systematic review included 87 articles with 119 patients of post-cardiac surgery chylopericardium. Chylopericardium developed after operations for congenital heart defect more than those for acquired heart disease, and more ...

Download PDF Read Full Article


Reliability and Validity of WATCH: Warwick Assessment InsTrument for Clinical TeacHing

By Sonia Ijaz Haider, Khalid Masood Gondol, Muhammad Tariq, Muhammad Furqan Bari, Iqbal Azam

ABSTRACT Objective: To determine the reliability, validity, feasibility, acceptability and perceived educational impact of WATCH: Warwick Assessment insTrument for Clinical teacHing among doctors in Pakistan. Study Design: Cross-sectional research study. Place and Duration of Study: The College of P...

Download PDF Read Full Article


Acute Side Effects with High Dose Rate Computed Tomography-guided Three-dimensional Brachytherapy in Carcinoma Cervix

By Sadia Sadiq, Abubaker Shahid, Misbah Masood, Rab Nawaz Maken, Amira Shami, Ismat Fatima

ABSTRACT: Objectives: To determine the frequency and grades of acute side effects with three-dimensional brachytherapy in carcinoma cervix using RTOG/EORTC acute radiation morbidity scoring criteria. Study Design: Descriptive study. Place and Duration of Study: Department of Radiotherapy, Institute ...

Download PDF Read Full Article


Expression of p53 Protein in Prostate Carcinoma and its Correlation with Gleason Grade

By Zakia Wahid, Rozina Jaffer, Sobia Khalid, Haseeb Ahmed Khan, Sabiha Riaz

ABSTRACT Objectives: To determine the correlation of p53 expression with Gleason score in prostate cancer. Study Design: Descriptive study. Place and Duration of Study: Department of Pathology, Fatima Memorial Hospital, Lahore; from January 2014 to August 2016. Methodology: Thirty-seven samples of ...

Download PDF Read Full Article


Mechanical Jaundice and Bile Duct Stricture Caused by the Migration of Endoclip and Silk Suture Material into the Common Bile Duct

By Şükrü Çolak, Hasan Bektaş, Bünyamin Gürbulak

ABSTRACT It is quite rare the migration of metal clips and silk suture materials into the common bile duct (CBD) that were used for the closure of cystic duct in conventional or laparoscopic cholecystectomy. The most common cause of postoperative jaundice is unrecognised or overlooked stones in...

Download PDF Read Full Article


Mesenteric Lipoma with Volvulus: A Rare Cause of Acute Abdomen in a Child

By Hamza Malik, Bilal Mirza, Nabila Talat, Waseem Zia, Anum Manzoor

ABSTRACT Lipoma is benign tumor of mature fat cells and is reported to develop anywhere in the body, e.g. trunk and extremities; however, lipoma in the mesentery of gut is rare, particularly in children. Mesenteric lipomas may be asymptomatic or may present with acute abdomen by leading to volvulus ...

Download PDF Read Full Article


Harlequin Fetus in a Twin Pregnancy: An Extremely Rare Presentation

By Arfan ul Bari, Syed Umair Ahmed Najmi

ABSTRACT Harlequin ichthyosis (HI) is a rare fatal type of congenital ichthyosis with autosomal recessive inheritance pattern. We report an uncommon presentation of a case of HI in a neonate, who was the second outcome of the dizygotic twin pregnancy of a Pakistani female. Whilst the first twin rema...

Download PDF Read Full Article


Late Diagnosis of Paracetamol Poisoning is Always Lethal in Young Adult

By Sehrish Naz, Safia Fatima, Muhammad Aamir

ABSTRACT Acetaminophen has a remarkable safety profile when prescribed in proper therapeutic doses, but hepatotoxicity can occur when misused or after an overdose. The principal toxic metabolite of acetaminophen is N-acetyl-p-benzoquinone imine (NAPQI). Toxicity should be considered in all suspiciou...

Download PDF Read Full Article


ROC Curve in Evaluation of Diagnostic Value of Serum 25-hydroxyvitamin-D for PCOS with Depression

By Ying Liu, Qianhui Qi

ABSTRACT The objective of this study was to apply receiver operating characteristic (ROC) curve to evaluate diagnostic value of serum 25-hydroxyvitamin-D [25-(OH)D] for polycystic ovarian syndrome (PCOS) combined with depression. Serum 25-(OH)D level was determined in 106 PCOS patients. Beck depress...

Download PDF Read Full Article


Association of Programmed Death Ligand-1 Overexpression with the Grade and Stage of Oral Squamous Cell Carcinoma

By Zeeshan Mustafa Qureshi, Samina Qamar

ABSTARCT Programmed Death Ligand-1(PD-L) expression can be used to predict targeted therapy against PD-L1/PD-1 pathway in oral squamous cell carcinoma (OSCC). Forty-nine patients were included in the study. Out of the total, 42 well differentiated tumor 3 (7.1%) exhibited strong PD-L1 membranous and...

Download PDF Read Full Article


A Case of Breakthrough Pain Management with Subcutaneous Fentanyl Administration in a Female Child

By Irum Ghafoor, Adeel Siddiqui, Haroon Hafeez, Hafiz Muhammad Usman

Download PDF Read Full Article


Mesenteric Hematoma: Challenges in Diagnosis and Management

By Kamal Kant Sahu, Ajay Kumar Mishra, Amos Lal, Iryna Chastain

Download PDF Read Full Article


Twin Pregnancy Complicated by Intrauterine Death of One Fetus and Herniated Bowel Loops Over Gravid Uterus

By Malika Hameed, Khalid Ahsan

Download PDF Read Full Article


Pistol Bullets: Not Fired But Ingested by a Patient of Borderline Personality Disorder

By Sana Khan, Usama bin Zubair, Rashid Qayyum, Nomita Sohail

Download PDF Read Full Article


Clinical Audit a Valuable Tool for Quality Improvement of Care: Radiation Oncologists’ Perspective

By Sehrish Abrar, Ahmed Nadeem Abbasi, Maria Tariq

Download PDF Read Full Article


A Dangerous Octopus Fishing: Kounis Syndrome Following an Octopus Bite

By Riccardo Scagliola, Gianluca Secchi, Claudio Brunelli

Download PDF Read Full Article


Special Issue

Special Supplement 1 on COVID-19 | Volume 30 | Year 2020
Tumor Boards during COVID-19 Pandemic

By Ahmed Nadeem Abbasi

Read Full Article


COVID-19 and Kidney Disease: Update on Epidemiology, Clinical Manifestations, Pathophysiology and Management

By Masoumeh Asgharpour, Elham Zare, Muhammed Mubarak, Amirhesam Alirezaei

Read Full Article


Psychological Status of Healthcare Workers during the Covid-19 Pandemic

By Tuba Talo Yildirim, Osman Atas, Azad Asafov, Kadir Yildirim, Hakan Balibey

Read Full Article


Pakistan’s Health System Against COVID-19: Where Do Things Stand?

By Meesha Iqbal, Aysha Zahidie

Read Full Article


Worsening of the COVID-19 Pandemic in New York City: Analysis of Response Gaps and Challenges at the Public Policy and Community Levels

By Aysha Zahidie, Meesha Iqbal, Syed Wasif Hussain

Read Full Article


A Case of 45-Year Man Who Succumbed to Coronavirus Disease 2019 (COVID-19)

By Muhammad Ahmed Khan, Muhammad Ameen Khan

Read Full Article


Diarrhoea: An Atypical Presentation of COVID-19

By Saad Khan, Zeeshan Ahmad, Fahad Khan, Hamza Asif, Asma Zia-ur-Rahman

Read Full Article


COVID-19 Pulmonary Infection with Pneumothorax in a Young Patient

By Okan Gurkan, Ayhan Yilmaz, Ferhat Cengel, Elif Sargin Altunok, Elif Evrim Ekin

Read Full Article


Optimising Ventilator Use during the COVID-19 Pandemic

By Sadaf Sheikh, Muhammad Akbar Baig

Read Full Article


CT Scan Findings of Five Mildly Symptomatic COVID Patients from India

By Sanjith Saseedharan, Vaijanti Kadam, Roopa Karanam, Paritosh Baghel

Read Full Article


Insight into COVID-19 Responses and Initiatives from Pakistan

By Salima Farooq, Sonia Ijaz Haider, Saima Sachwani, Yasmin Nadeem Parpio

Read Full Article


Chest CT Findings of Coronavirus Disease 2019 (COVID-19)

By Wu Cai, Junlin Yang, Guohua Fan, Liang Xu, Bo Zhang, Rong Liu

Read Full Article


The Rapid COVID Screening (RCS) Tool

By Muhammad Akbar Baig

Read Full Article


Mental Health Challenges and Psycho-social Interventions amid COVID-19 Pandemic: A Call to Action for Pakistan

By Salima Muhammad Farooq, Saima Abdul aziz Sachwani, Sonia Ijaz Haider, Sajid Abrar Iqbal, Yasmin Nadeem Parpio, Humera Saeed

Read Full Article


Dermatology Residency Training in COVID-19 Pandemic: Transition from Traditional to Online Teaching

By Arfan ul Bari

Read Full Article


Challenges of Online Medical Education in Pakistan During COVID-19 Pandemic

By Fareeha Farooq, Farooq Azam Rathore, Sahibzada Nasir Mansoor

Read Full Article


Silent Hypoxia in COVID-19: What is Old is New Again!

By Sadaf Sheikh, Muhammad Akbar Baig

Read Full Article


Emergency Preparedness and Response to the COVID-19 Pandemic: Our Experience from the Emergency Department of a Tertiary Care Hospital in Pakistan

By Badar Afzal, Noman Ali, Asad Mian

Read Full Article


COVID-19 Pandemic: Public Trust and Guiding Ethics Where Ventilators Equal Lives

By Sadaf Sheikh, Muhammad Akbar Baig

Read Full Article


A Rare Finding of Upper Limb Deep Venous Thrombosis in a Patient with COVID-19

By Shankar Lal, Junaid Hashmi

Read Full Article


Chloroquine and Hydroxychloroquine in COVID-19: Challenges and the Need for Caution in Low-Resource Settings

By Mahnoor Islam

Read Full Article


COVID-19 Pandemic: Are Patients with Inflammatory Bowel Disease Really at Risk?

By Syed Adeel Hassan, Jude Ezeh

Read Full Article


COVID19: A Matter of State and Faith

By Abuzar Siraj, Zair Hassan, Muhammad Shahbaz Khan

Read Full Article


Precautions in the Operating Room during COVID-19 Pandemic

By Kazim Hussain, Salman Javed, Syed Ali Anwer Jillani

Read Full Article


The Impact of COVID-19 on the Mental Health of Healthcare Professionals

By Muhammad Ali Awab Sarwar, Huda Sarwar

Read Full Article


Contributions and Challenges of Radiology in the Era of COVID‐19 Pandemic

By Mahnoor Hafeez, Amjad Sattar

Read Full Article


Urgent, Emergent, or Elective Surgery during the COVID-19 Pandemic

By Vasileios Karampelias, Ypatios Spanidis, Constantinos D. Zografos

Read Full Article


Convalescent Plasma: Promise for COVID-19 Pandemic

By Sadaf Sheikh, Muhammad Akbar Baig

Read Full Article


COVID-19 and Impending Shortage of Haemodialysis Facilities due to the Rising Incidence of Acute Kidney Injury Requiring Renal Replacement Therapy

By Raheel Ahmed, Abdul Haseeb

Read Full Article


A Systematic Analysis of Studies on Corona Virus Disease 19 (COVID-19) from Viral Emergence to Treatment

By Shahzadi Misbah, Abrar Ahmad, Muhammad Hammad Butt, Yusra Habib Khan, Nasser Hadal Alotaibi, Tauqeer Hussain Mallhi

Read Full Article


Impact of Urbanisation on COVID-19: Diversity in Virulence

By Muhammad Hammad Athar, Usama Bin Zubair, Ayesha Habib

Read Full Article