Journal of College of Physicians and Surgeons Pakistan (JCPSP), is the prestigious, peer reviewed monthly biomedical journal of the country published regularly since 1991. College of Physicians and Surgeons Pakistan is the parent body of this Journal.


The College of Physicians and Surgeons of Pakistan (CPSP) is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide credits to educational activities.

CPSP designates '3 AMA PRA Category 1 Credits' for review of the manuscript of an original study.


Latest Articles
Volume 29 | Issue 6 | June 2019
New Tools for an Old Disease: Endovascular Treatment for Varicose Veins

By Zia Ur Rehman

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Outcomes of Left Main Percutaneous Coronary Intervention

By Muhammad Nasir Rahman, Bilal Hussain, Azmina Artani

Objective: To study the outcomes of left main percutaneous coronary artery (LMCA) revascularisation. Study Design: A descriptive study. Place and Duration of Study: The Aga Khan University Hospital (AKUH), Karachi, from February till July 2016. Methodology: The study included all adult patients a...

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Combination of Oral Tranexamic Acid with Topical 3% Tranexamic Acid versus Oral Tranexamic Acid with Topical 20% Azelaic Acid in the Treatment of Melasma

By Fahmida Malik, Malik Muhammad Hanif, Ghulam Mustafa

Objective: To compare the effect of combination therapies of topical 3% tranexamic acid versus topical 20% azelaic acid each combined with oral tranexamic acid in the treatment of melasma. Study Design: Interventional comparative study. Place and Duration of Study: Department of Dermatology, Shei...

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Accessibility to Healthcare and Risk of Polypharmacy on Chronically ill Patients

By Suleyman Ersoy, Velittin Selcuk Engin

Objective: To investigate the rates of polypharmacy (PP) and its relations with accessibility to health services in chronic patients in a primary care setting. Study Design: A cross-sectional study. Place and Duration of Study: Melekhatun Family Health Center, Istanbul, Turkey, from January 2014 ...

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Effect of Dexketoprofene Trometamol on Post-Endoscopic Retrograde Cholangiopancreatography Pancreatitis

By Aziz Ari, Bunyamin Gurbulak, Hasan Okmen, Cihad Tatar, Ufuk Oguz Idiz, Muhammed Zubeyr Ucuncu

Objective: To evaluate the efficacy of dexketoprofene trometamol solution following the administration of contrast agent for Endoscopic Retrograde Cholangiopancreatography (ERCP) in decreasing the rate of pancreatitis, in experimental rat model. Study Design: Experimental study. Place and Duratio...

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Effectiveness of Direct Observation of Procedural Skills (DOPS) in Postgraduate Training in Urology at Institute of Kidney Diseases, Peshawar

By Liaqat Ali, Saima Ali, Nasir Orakzai, Naila Ali

Objective: To determine the effectiveness of direct observation of procedural skills (DOPS) in the assessment and improving operative skills of postgraduate residents in urology. Study Design: Comparative study. Place and Duration of Study: Department of Urology, Institute of Kidney Diseases (IKD...

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Evaluation of Thin Layer Agar 7H11 for Direct Susceptibility Testing of Mycobacterium Tuberculosis Complex against Second Line Anti Tuberculosis Drugs on Smear Positive Specimens

By Ashfaq Hussain, Gohar Zaman, Luqman Satti, Aamer Ikram, Adeel Hussain Gardezi, Muhammad Tahir Khadim

Objective: To evaluate performance of thin layer agar (TLA) 7H11 method for detection of ofloxacin (OFX) and kanamycin (KM) resistance in smear positive clinical specimens of patients with tuberculosis comparing the results with gold standard MGIT 960 system. Study Design: Cross-sectional validat...

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Is Adenotonsillar Size a Significant Factor on Voice in Children Undergoing Adenotonsillectomy?

By Suleyman Emre Karakurt, Mehmet Ali Cetin, Ali Riza Yamur, Aykut Ikinciogullari, Serdar Ensari, Haci Huseyin Dere

Objective: To determine whether adenotonsillar size is a significant determinant of voice in children who have undergone adenotonsillectomy. Study Design: Prospective cohort study. Place and Duration of Study: Ear Nose Throat Clinic, Ankara Numune Training and Research Hospital, Ankara, Turkey, ...

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Effects of Parecoxib on Pain Threshold and Inflammatory Factors IL-1β, IL-6 and TNF-𝜶 in Spinal Cord of Rats with Bone Cancer Pain

By Jun Chen, Xiufeng Cong, Xiuzhu Zhan, Zheng Zhou, Wei Zheng

Objective: To investigate the effects of parecoxib on pain threshold and inflammatory factors interleukin-1β (IL-1β), interleukin-6 (IL-6) and tumor necrosis factor-α (TNF-α) in spinal cord of rats with bone cancer pain. Study Design: An experimental study. Place and Duratio...

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Inhibitory Effect of Semen Litchi Drug Serum on the Proliferation of Human Hepatoma HepG2 Cells and Expression of VEGF and MMP-9

By Lichun Zhao, Peiliang Yu, Tao Yang, Gailian Zhou, Nong Tang

Objective: To investigate inhibitory effect of semen litchi drug serum on proliferation of human hepatoma HepG2 cells and its effect on the expression of vascular endothelial growth factor (VEGF) and matrix metalloproteinase-9 (MMP-9). Study Design: An experimental study. Place and Duration of St...

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Effect of Dexamethasone on TGF-β1/Smad3 Signalling Pathway in Airway Remodelling Model of Asthmatic Rats

By Yan Feng, Chang Yang, Wen Yang, Tao Jiang

Objective: To determine the effect of dexamethasone on regulating the TGF-β1/Smad3 signalling pathway in airway remodelling model of asthmatic rats. Study Design: An experimental study. Place and Duration of Study: Department of Pathology, The First Hospital of Wuhan, Hubei Province, China, ...

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Relationship between the Quality of Sleep and Psychiatric Morbidity among the Patients of Head and Neck Tumours

By Usama Bin Zubair, Humza Mumtaz, Rizwan Taj

Objective: To assess the difference between mean sleep (PSQI) scores in the patients with head and neck tumours with and without the psychiatric morbidity; and assess the associated socio-demographic factors. Study Design: Descriptive cross-sectional study. Place and Duration of Study: Pakistan I...

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Application of Non-invasive Positive Pressure Ventilation Combined with PetCO₂ Monitoring for Patients with Chronic Obstructive Pulmonary Disease Combined with Severe Respiratory Failure

By Fu-Tao Cao, Yu Cui, Jia Mao, Fang Wan, Su Tu

Objective: To investigate the role of PetCO₂ monitoring in non-invasive positive pressure ventilation (NPPV) treatment for chronic obstructive pulmonary disease (COPD) patients combined with severe respiratory failure. Study Design: A clinical retrospective study. Place and Duration of Study: T...

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A Single Institution's Experience with Cytogenetic and MRD Outcomes in Pediatric Acute Lymphoblastic Leukemia

By Asim Amjad, Rabia Muhammad Wali, Sadia Anjum, Raheela Mansoor

Objective: To determine the frequency of cytogenetic type and its significance in the prognostic outcome of the pediatric patients in acute lymphoblastic leukemia (ALL), aged 1 to 15 years, and also determine the importance of minimal residual disease (MRD) in the management of the condition. Stu...

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Spectrum of Biopsy Proven Extraocular Muscle Tumours of Non-Thyroid Origin

By Tayyab Afghani, Hassan Mansoor, Amna Manzoor Mughal, Mohammad Asif, Muhammad Asif, Naeem Raza Hamdani

Objective: To describe different types of primary extraocular muscle (EOM) tumours based on the results of imaging studies, peroperative clinical picture and their histopathological diagnosis. Study Design: Case series. Place and Duration of Study: Al-Shifa Trust Eye Hospital, Rawalpindi, from Ju...

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Risk Factors for Infectious Complications in Patients Undergoing Retrograde Intrarenal Surgery

By Demirhan Orsan Demir, Omer Gokhan Doluoglu, Yildiray Yildiz, Selen Bozkurt, Ali Ayyildiz, Arif Demirbas

Objective: To investigate the risk factors that may cause urinary tract infection (UTI) in patients applied with retrograde intrarenal surgery (RIRS). Study Design: An observational study. Place and Duration of Study: Departments of Urology, Ankara Training and Research Hospital, Turkey, from Sep...

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Scoping Review of Crimean-Congo Hemorrhagic Fever (CCHF) Literature and Implications of Future Research

By Braira Wahid, Saba Altaf, Nabiha Naeem, Nimra Ilyas, Muhammad Idrees

Crimean-Congo hemorrhagic fever (CCHF) is one of the severe forms of high-fatality hemorrhagic fever transmitted by bite of infected ticks or body fluids of infected individuals. Lack of sufficient research and endemic potential of the disease is posing serious threats to public health. The aim of...

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Presternal Goiter

By Matheo Augusto Morandi Stumpf, Andre Scartezini Marques, Ana Claudia Garabeli Cavalli Kluthcovsky, Camila Gabriella da Costa Belonci

An enlarging thyroid normally extends into the mediastinum, resulting in a presternal or substernal goiter, depending on its migration anteriorly or posteriorly, respectively. The first one was a rare entity in medical literature, being previously reported in only 6 cases worldwide. The present ca...

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Metastatic Carcinoma of Endometrium from Primary Ovarian Serous Carcinoma Mimicking a Primary Uterine Tumour

By Mengfei Xu, Feng Zhou, Lili Huang

A 44-year female was admitted to the hospital, complaining of vaginal bleeding. Ultrasound imaging revealed two masses in the pelvic cavity, measuring 6.6 x 3.4 x 1.8 cm and 8.2 x 4.7 x 3.7 cm in size. After surgical debulking of the tumours, the patient underwent abdominal hysterectomy, bilateral...

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Post-tuberculosis Pneumocytoma

By Mustafa Kupeli, Hakan Nomenoglu

Pneumocytoma is a rare benign tumor of the lung that usually manifests as a solitary pulmonary nodule. A 69-year lady, who had history of tuberculosis treatment 20 years ago, admitted to the hospital. A round mass was seen on chest radiography. Thorax computed tomography was reported as a round le...

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Malakoplakia of the Urinary Bladder and Unilateral Ureter

By Saddaf Hina, Aisha Hasan, Nadeem Iqbal, Muhammad Usman Shabbir, Abdul Ahad Ehsan Sheikh

Malakoplakia is an unusual acquired granulomatous disease that can affect many systems including urogenital tract. It presents a huge diagnostic challenge as it can mimic malignancy. We report a 55-year diabetic woman who presented with history of macroscopic hematuria and right flank pain. On inv...

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Expression and Significance of miR-126 and miR-145 in Infertility due to Endometriosis

By Fang Cheng, Luyan Lu, Huixia Wang, Hong Cheng, Dawei Zhang

The aim of this study was to determine the expression and significance of miR-126 and miR-145 in endometrial tissues in the mid-luteal phase of patients with infertility due to endometriosis. It was an experimental study carried out from January 2016 to July 2017. A total of 47 infertile patients ...

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Female Peritoneal Tuberculosis with Ascites, Pelvic Mass, or Elevated CA 125 Mimicking Advanced Ovarian Cancer: A Retrospective Study of 26 Cases

By Haijiao Wang, Xinglong Qu, Xiaoxia Liu, Lili Ding, Ying Yue

This study aimed to summarise the clinical experience of peritoneal tuberculosis (TB). Clinical data of 26 patients admitted and diagnosed with peritoneal TB mimicking advanced ovarian cancer or peritoneal carcinoma between June 2008 and June 2017, was evaluated. The mean age was 35.92 ±15....

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Severe Growth Failure and Poorly Controlled Type 1 Diabetes Mellitus in a 7-Year-Old Girl: Mauriac Syndrome

By Saima Gillani, Attia Iqbal, Nasir Hussain Shah Kazmi

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Stethoscope as a Vector for Nosocomial Bacterial Infections

By Rehana Rehman, Khalid Ahmed, Saifullah Shaikh

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Intraparotid Tuberculosis Misdiagnosed as Neoplasm on FNAC

By Tahir Muhammad, Haissan Iftikhar, Mubasher Ikram

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Effect of Aspirin on Reducing Thrombosis of Arteriovenous Fistulae in Uremic Patients Undergoing Hemodialysis

By Hui Liu, Huijun Lu

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Special Issue

Special Supplement 1 | Volume 29 | June 2019
Case Reports – Special Supplement

By Editor JCPSP

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Growth Hormone and ACTH Deficiency in a Diabetic Adult

By Asif Ali Memon, Mehwish Gilani, Naveed Asif, Nida Basharat

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A Case of Dynamic Evolution of Thyrotoxicosis on Follow-up

By Cong Qing Miao, De Chuan Lu, Jing Jing Liu, Hui Xu, Xin Long Meng

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Coexistence of Papillary Thyroid Cancer and Primary Hyperparathyroidism: Report of Five Cases

By Hasan Calis, Nuraydin Ozlem, Serif Melih Karabeyoglu

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Primary Supraclavicular Cystic Lymphangioma in an Adult: A Rare Presentation

By Mansoor Tariq Azim, Syed Mukarram Hussain, Mohammad Awais Mughal

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An Adult Case of Thiamine-Sensitive Megaloblastic Anemia Syndrome Accidentally Diagnosed Myelodysplastic Syndrome

By Ali Kutlucan

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Endothelial Cysts of Adrenal Gland

By Zafar Ali, Hina Tariq, Usama Rehman

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JC Virus Infection: A Clinical Conundrum

By Hajra Farooq, Saifullah Khan Niazi, Misbah Noor, Eijaz Ghani

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Gastric Tuberculosis

By Naresh Kumar Seetlani, Khalid Imran, Qurat ul Ain Hafeez, Asif Ali, Pyar Ali Fazil, Bareeha Shaukat Sultan, Sulhera Khan

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Congenital Erythropoietic Porphyria: A Rare Case of Photosensitivity with Hemolytic Anaemia and Mental Retardation

By Nadia Shirazi, Payal Chauhan, Rashmi Jindal, Sohaib Ahmad

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Ischemic Skin Necrosis in Hepatorenal Syndrome Patient Secondary to Terlipressin

By Raheel Ahmed, Abdul Haseeb

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Adult-Onset Subacute Sclerosing Panencephalitis Presented with Neuropsychiatric Symptoms

By Abdulkerim Gokoglu, Hasan Tahsin Gozdas

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Primary Extra-renal Wilms' Tumor in Urinary Bladder: Rare Presentation of a Common Pediatric Malignancy

By Irfana Ishaq Sindhu, Haleema Saeed, Rabia Wali, Asma Mehreen

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Ocular Cicatricial Pemphigoid: Camouflaged as Persistent Conjunctivitis

By Jamal-uddin Mughal, Asif Jan Muhammad, Uzma Erum

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Traboulsi Syndrome in Pakistan

By Tehmina Awais, Mehmood Ali, Saad Alam Khan

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Shprintzen-Goldberg Syndrome: A Rare Disorder

By Attia Bari, Nadia Sadaqat, Nadia Nawaz, Iqbal Bano

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Primary Pulmonary Hypertension Associated with Asymptomatic Methylmalonic Aciduria in a Child

By Fatma Zohra Chioukh, Kamel Monastiri

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Primary Iliopsoas Abscess in a Neonate

By Muhammad Umar Nisar, Samer Sikander, Zenab Noorain, Mehr-un-Nisa Shahid Baig, Nadeem Akhtar

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A Rare Cause of Intractable Diarrhea of Infancy

By Salman Ali, Aroma Tariq, Maryam Ghuncha

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A Neonate with Upper GI Bleeding

By Suneeta Khemani, Huma Ghulam Qadir, Mumtaz Malik, Faiqa Hassan

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A Child with Weight Loss and Alacrimation: Triple A Syndrome

By Qurat ul Ain, Naveed Asif, Noreen Shahzad, Waqas Hanif Sheikh

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A Child with Ambiguous Genitalia: An Atypical Presentation

By Waqas Hanif Sheikh, Naveed Asif, Muhammad Younas, Nida Basharat, Qurat-ul-Ain , Noreen

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Erotomania in Depressive Psychosis: Mood Incongruent Delusion in a Depressive Young Woman

By Usama Bin Zubair, Sawera Mansoor

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Polyarthritis as the Initial Presentation of Hyper Eosinophilic Syndrome

By Lubna Nazir, Amir Riaz, Hamza Alam

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Bladder Hernia, Bladder Stone and Contralateral Bowel Hernia: An Usual Combination

By Akif Erbin, Halil Lutfi Canat, Burak Ucpinar, Hayati Malcik

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Adrenal Myelolipoma with Adrenocortical Adenoma Presenting with Hypertension Only

By Fan Yang, Chenyu Sun, Shiyu Pang, Juanjuan Cai, Hao Lin, Wanlong Tan

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Neoaorta Reconstruction Using Both Femoral Veins in a Patient with Secondary Aortoenteric Fistula

By Zia-ur Rehman

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Detection and Management of Pregnancy in Rudimentary Horn of Uterus

By Rizwana Parveen

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