Journal of College of Physicians and Surgeons Pakistan (JCPSP), is the prestigious, peer reviewed monthly biomedical journal of the country published regularly since 1991. College of Physicians and Surgeons Pakistan is the parent body of this Journal.

The College of Physicians and Surgeons of Pakistan (CPSP) is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide credits to educational activities.

CPSP designates '3 AMA PRA Category 1 Credits' for review of the manuscript of an original study.

Important Announcement for Authors

"As a large number of case reports are awaiting publication, JCPSP has decided to stop acknowledging Case Reports for a certain period of time until the backlog is cleared. Therefore, case reports are regretted from processing".

Latest Articles
Volume 31 | Issue 2 | February 2021
Rising Trend of Women in Gastroenterology: A Paradigm Shift

By Lubna Kamani, Jeanin E Van Hooft

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Association of Early-onset Androgenetic Alopecia and Metabolic Syndrome

By Fatima Zia Sheikh, Ghazala Butt, Rukhsha Hafeez, Aiman Maqsood, Faria Altaf, Ijaz Hussain

ABSTRACT Objective: To evaluate the association of early-onset AGA (androgenetic alopecia) and metabolic syndrome in the younger male population. Study Design: Case-control study. Place and Duration of Study: Department of Dermatology, Mayo Hospital Lahore, from October 2017 to March 2018....

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Concomitant Therapy versus Triple Therapy: Efficacy in H. Pylori Eradication and Predictors of Treatment Failure

By Abdul Moeez Kaiser Butt, Shahid Sarwar, Muhammad Arif Nadeem

ABSTRACT Objective: To compare concomitant therapy (CT) and triple therapy (TRT) for success in helicobacter (H.) pylori eradication and identify factors associated with treatment failure. Study Design: Quasi-experimental comparative study. Place and Duration of Study: Department of Medicine and Gas...

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Is Spontaneous Pneumomediastinum a Poor Prognostic Factor in Covid-19?

By Ibrahim Ethem Ozsoy, Mehmet Akif Tezcan, Seda Guzeldag, Ayse Turunc Ozdemir

ABSTRACT Objective: To determine the risk factors for spontaneous pneumomediastinum (SPM), its clinical course and effect on prognosis in patients with Coronavirus disease-19 (COVID-19) pneumonia. Study Design: Descriptive study. Place and Duration of Study: Kayseri City Training and Research Hospit...

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Arterial Stiffness and its Related Factors in Patients on Hemodialysis

By Burkay Yakar, Mustafa Demir, Erhan Onalan, Mehmet Onur Kaya

ABSTRACT Objective: To evaluate the prevalence of arterial stiffness in patients on hemodialysis and related factors that aggravate the condition. Study Design: Prospective-cohort study. Place and Duration of Study:  Department of Nephrology, Firat University Hospital, Turkey, from August to O...

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Pulmonary Functions in Patients with End Stage Renal Disease and their Effect after Hemodialysis

By Muhammad Anees, Saleem uz Zaman Adhami, Muhammad Aamer, Imran Shahid

ABSTRACT Objective: To determine the pulmonary functions in patients with End Stage Renal Disease (ESRD) and the associated factors including the acute effects of hemodialysis. Study Design: Observational, cross-sectional study.   Place and Duration of Study: Nephrology Department in collaborat...

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Correlation of Breast Cancer Subgroups and Axillary Metastases with 18F-FDG PET/CT and the Contribution of 18F-FDG PET/CT in the Management of the Axilla

By Nazmi Ozer, Abdullah Sahin

ABSTRACT Objective: To investigate whether breast and axilla maximum standard uptake (SUVmax) values contribute to the treatment approach in breast cancer subgroups. Study Design: A descriptive study. Place and Duration of Study: University of Health Sciences/Adana City Training and Research Hospita...

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Pre-treatment Delta Neutrophil Index as a Predictive Factor in Renal Cell Carcinoma

By Osman Barut, Mehmet Kutlu Demirkol, Faruk Kucukdurmaz, Tayfun Sahinkanat, Sefa Resim

ABSTRACT Objective: To determine the diagnostic value of the pre-treatment delta neutrophil index (DNI) before treatment in patients with renal cell carcinoma (RCC) and to compare this marker with other routine inflammation markers, such as neutrophil-lymphocyte ratio (NLR) and platelet-lymphocyte r...

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Comparison of Retinal Nerve Fibre Layer versus Bruch Membrane Opening-Minimum Rim Width as an Optical Coherence Tomography-based Marker for Glaucoma in Myopia

By Najia Uzair, Mariam Shamim, Syed Asaad Mamoon, Saliha Naz, Lubna Feroz, Komalta Kumari

ABSTRACT Objective: To compare the reliability of Bruch Membrane Opening-Minimum Rim Width (BMO-MRW) Optical Coherence Tomography (OCT) with Retinal Nerve Fibre Layer (RNFL) in myopic patients. Study Design: Cross-sectional study. Place and Duration of Study:  LRBT Free Base Eye Hospital, Karac...

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Clinical Outcomes and Prognostic Factors in HER-2 Positive Breast Cancer with Brain Metastasis: A Single-centre Experience

By Serdar Karakaya, Ibrahim Karadag, Ozturk Ates, Omur Berna Cakmak Oksuzoglu, Umut Demirci

ABSTRACT Objective: To determine the characteristics and prognosis of brain metastasised HER-2 positive breast cancer (BC) patients. Study Design: Descriptive study. Place and Duration of Study: Ankara Oncology Training and Research Hospital, Turkey between 2000 and 2019. Methodology: HER-2 pos...

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Scale Development Study: Readiness for Discharge from the Neonatal Intensive Care Unit and Home Care of Premature Infants by Parents

By Oznur Tiryaki, Nursan Cinar

ABSTRACT Objective: To develop the readiness for hospital discharge scale for mothers and fathers with a premature infant hospitalised in the neonatal intensive care unit and to test the validity and reliability of this scale. Study Design: A cross-sectional study. Place and Duration of Study: Sakar...

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Predictive Value of Betatrophin for Determining the Cardiovascular Risks of Obese Individuals

By Nazli Haciagaoglu, Huseyin Cetin, Ozlem Hurmeydan, Engin Ersin Simsek

ABSTRACT Objective: To determine cardiovascular risk factors, calculate cardiovascular risk, and the value of betatrophin, a novel biomarker in predicting the risk of cardiovascular disease (CVD) in obese individuals. Study Design: Cross-sectional and descriptive study. Place and Duration of Study:...

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The Effect of COVID-19 Pandemic on Performance of Postgraduate Medical Trainee Doctors: A Nationwide Epidemiological Study in Pakistan

By Saira Afzal, Muhammad Hasan Masood, Fariha Salman, Khalid Masud Gondal, Amber Arshad

ABSTRACT Objective: To find out various organizational, personal, and systemic factors influencing the performance of the postgraduate trainee doctors in managing COVID-19 pandemic. Study Design: Analytical cross-sectional study. Place and Duration of Study: Conducted in various medical institution...

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Can First-trimester AST to Platelet Ratio Index Scores Predict HELLP Syndrome?

By Harun Egemen Tolunay, Neval Cayonu Kahraman, Erol Nadi Varli, Yildiz Akdas Reis, Sevki Celen, Ali Turhan Caglar

ABSTRACT Objective: To determine whether the ratio of the first-trimester aspartate aminotransferase (AST) to platelet ratio index (APRI) score will be useful as a new determinant of hemolysis, elevated liver enzymes, low platelets (HELLP) syndrome that may develop in the later stages of pregnancy S...

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Factors Affecting Cervical Lymph Node Suppuration in Oropharyngeal Tularemia Cases

By Nevin Ince, Hasan Tahsin Gozdas

ABSTRACT Objective: To determine the factors associated with cervical lymph node suppuration in oropharyngeal tularemia. Study Design: Observational study. Place and Duration of Study: Departments of Infectious Diseases and Clinical Microbiology, Faculties of Medicine, Duzce University and...

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Renal Allograft Biopsy Findings in Live-related Renal Transplant Recipients

By Syed Munib, Tanveer Ahmed, Raheel Ahmed, Najam-ud-Din

ABSTRACT Objective: To determine the pattern of histopathology in living-related, kidney transplant recipients (KTRs) from a transplant centre in Khyber Pakhtunkhwa (KPK), Pakistan. Study Design: Descriptive, observational study. Place and Duration of Study: Institute of Kidney Diseases, Pesha...

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Assessing the Adherence of Operative Notes for Laparoscopic Appendectomy with the Royal College of Surgeons Guidelines

By Fatima Mannan, Roger Christopher Gill, Abdul Ahad Sohail, Rehman Alvi

ABSTRACT  Objective: To determine the frequency of adherence of laparoscopic appendectomy operative notes with the Royal College of Surgeons (RCS) guidelines at the tertiary care centre.  Study Design: A clinical audit report. Place and Duration of Study: The Aga Khan University Hospital, ...

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Efficacy of Standardised Treatments Combined with Ubenimex in Patients with Malignant Tumors

By Xin Hu, Haofeng Xiong, Shiying Huang, Ting Mao, Liudi Yang, Tong Su

ABSTRACT Ubenimex is widely used as an immunomodulator in the treatment of leukemia and non-small cell lung cancer to improve the anti-tumor treatment effect. However, there has not been any multicenter randomised controlled trials to study its impact on the prognosis of cancer patients. The authors...

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Impact of Intraoperative Dexmedetomidine versus Remifentanil on Recovery Characteristics following Laparoscopic Sleeve Gastrectomy

By Abdul Sattar Narejo, Muhammad Musa Khan, Ali Alwhabi, Adel Alqarni, Abdulaziz Ejaz Ahmed, Abdelazeem Ali Eldawlatly

ABSTRACT Objective: To evaluate the impact of intraoperative dexmedetomidine versus remifentanil on postoperative pain; and enhanced recovery profile in patients scheduled for laparoscopic sleeve gastrectomy (LSG). Study Design: Clinical observational double-blind pilot study. Place and Duration of ...

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Concurrent Arterial and Venous Thrombosis in a Patient with Ulcerative Colitis in Remission Phase

By Hamid Ali Kalwar, Tauqeer Shaikh, Muhammad Hussain Baloch

ABSTRACT Vascular thrombosis is an unusual yet well-known extra-intestinal complication of ulcerative colitis, usually involving the peripheral veins and occasionally the cerebral veins and the arterial system. We, herein, report a case of a 45-year female with ulcerative colitis in remitting p...

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Sarcoidosis Presenting as Fatigue and Weakness

By Syed Muhammad Zubair, Naveed Haroon Rashid

ABSTRACT Sarcoidosis is a systemic granulomatous disorder of unknown cause that occurs in both men and women of all races. It typically presents in patients after 20 years of age. Sarcoidosis most frequently involves the lung, but up to 30 percent of patients present with extra-thoracic manifestatio...

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Cortical Venous Thrombosis Complicating Tubercular Meningitis

By Jahnvi Dhar, Garvit Chhabra, Lokesh Khandelwal, S. Anuradha, Akshee Batra

ABSTRACT Cortical venous thrombosis (CVT) mostly occurs due to a hypercoagulable state. Infection- related CVT is very rare and is a medical emergency associated with a very high mortality rate. It has been described with bacterial and fungal infections; but only a few isolated case reports of CVT ...

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A Collision Tumor with Squamous Cell Carcinoma of Skin Overlying Breast and Invasive Breast Carcinoma

By Ozlem Ceren Gunizi, Hasan Calis

ABSTRACT Invasive breast cancer is the most common carcinoma in women. Invasive ductal carcinoma, not otherwise specified (NOS), is the largest group of invasive breast cancers. The second most common cancer of skin is squamous cell carcinoma (SCC). Collision tumor is a very rare and unusual tumor. ...

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An Old Enemy: Still Nephrotoxic

By Faruk Recep Ozalp, Tugba Karadeniz, Alper Alp

ABSTRACT Tubulointerstitial nephritis (TIN) presents histopathologically as tubulitis and oedema/inflammation and fibrosis, affecting the renal tubules and interstitium with relative sparing of the glomeruli and vasculature. It can be acute or chronic or acute on chronic and has a wide range of eti...

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Acute Hepatitis-A Virus Infection as a Rare Cause of Hemophagocytic Lymphohistiocytosis

By Ali Dogan, Sinan Demircioglu, Omer Ekinci

ABSTRACT Hemophagocytic lymphohistiocytosis (HLH) is a rare disorder of the mononuclear phagocytic system, characterised by histiocyte and lymphocyte activation. It can be classified as primary and secondary HLH. Primary HLH usually presents in childhood, and is associated with gene mutations. Secon...

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Rhabdomyolysis Leading to Acute Kidney Injury

By Sajad Ahmad, Muhammad Anees, Irfan Elahi, Fazal-e-Mateen

ABSTRACT Rhabdomyolysis constitutes an uncommon cause of acute kidney injury (AKI). A large variety of causes with different pathogenic mechanisms may involve skeletal muscles resulting in rhabdomyolysis with or without acute kidney injury. Crush syndrome and unaccustomed physical exertion are the m...

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Correlation between 1-FABP, Blood Routine and Grading of Necrotising Enterocolitis

By Wei Su, Yanjun Li, Yuebin Wang, Lixiang Li, Jianhui Yan

ABSTRACT Correlation was sought between serum intestinal fatty acid binding protein (I-FABP), blood routine examination indexes, and necrotizing enterocolitis (NEC) disease classification. According to Bell-NEC grade, 86 children with NEC were divided into mild group (46 cases) and severe group (40 ...

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Comparison of Efficacy of Teriparatide (Parathyroid Hormone 1-34) Alone and in Combination with Zoledronic Acid for Osteoporosis in Postmenopausal Women

By Kang Wei, Yuxing Qu, Yi Gao, Yong Ma

ABSTRACT The purpose of this study was to compare the efficacy of teriparatide (parathyroid hormone 1-34) alone and in combination with zoledronic acid (ZA) for the treatment of osteoporosis in postmenopausal women. Ninety-six patients were randomly equally divided into Groups A (n=48) and B (n=48)....

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Anaesthesia Management of a 6-year Child with Leigh Syndrome undergoing Strabismus Surgery

By Anwar Ul Huda, Mohammad Yasir

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Left Dominant Arrythmogenic Cardiomyopathy

By Muhammad Mohsin Sajjad, Kabir Ali, John Corrigan

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Iron Deficiency Anemia Induced Thrombocytopenia: A Report of Two Cases

By Metin Bağci, Batuhan Erdogdu, Mehmet Dagli, Abdulkadir Basturk

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Anaphylactic Shock due to Non-Ruptured Hydatid Cyst of Liver

By Akkan Avci, Begum Seyda Avci, Kemal Sener

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Diabetic Chorea: A Rare Complication of Poorly Controlled Diabetes Mellitus

By Buse Cagla ARI

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Special Issue

Special Supplement 1 on COVID-19 | Volume 31 | Year 2021
Predictors of Mortality in Patients with COVID-19 Infection-associated Acute Kidney Injury

By Aysel Tocoglu, Hamad Dheir, Melike Bektas, Seyyid Bilal Acikgoz, Oguz Karabay, Savas Sipahi

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Has the COVID-19 Pandemic Increased Mortality Among Patients with Cancer Receiving Systemic Anticancer Treatments?

By Ayşe Demirci, Cemil Bilir, Emre Cakir, Burcu Gulbagci, Ilhan Hacibekiroglu, Ceyhun Varim

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Outcomes of Conservative Management of Acute Appendicitis during COVID-19 Pandemic

By Muzna Iftikhar, Sajida Shah, Inamullah Shah, Jamil Ahmad Shah, Mahvish Faisal

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Comparison of HRCT Chest and RT-PCR in Diagnosis of COVID-19

By Nadia Hanif, Ghazala Rubi, Nadia Irshad, Saima Ameer, Uzma Habib, Syed Razi Haider Zaidi

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The Effect of Tocilizumab on Inflammatory Markers in Survivors and Non-survivors of Severe COVID-19

By Said Amin, Fawad Rahim, Sher Bahadur, Mohammad Noor, Afsheen Mahmood, Huma Gul

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Clinical Characteristics and Outcomes among Patients with Covid-19 in Different Regions of the World

By Yuanlin Zhou, Huihai Fan

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Online Medical Education and Examinations during COVID-19: Perspectives of a Teaching Associate

By Syed Mujtaba Baqir, Fatima Mustansir

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Short-term Changes on Follow-up Chest X-rays of Familial Cluster of COVID-19 Cases

By Chun-Xue Wu, Dong-Dong Rong, Yan-Hong An, Yi Shan, Jie Lu

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Right to Left Intrapulmonary Shunt in a Case with COVID-19-associated Pneumonia

By Maimoona Siddique, Muhammad Khalid Nawaz, Muhammad Bin Khalid, Aitzaz Rai

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Recurrence of COVID-19 Documented with RT-PCR

By Rohat Ak, Erdal Yilmaz, Avni Uygar Seyhan, Fatih Doganay

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COVID-19 Presenting with Spontaneous Pneumothorax

By Intisar Ahmed, Hunaina Shahab, Muhammad Arslan Ahmed, Muhammad Sohaib

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Protective Modifications in Ophthalmology Practice during COVID-19 Pandemic: Challenges and Lessons Learned

By Mohammad Idris, Eemaz Nathaniel

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Airway Management for Emergent Surgeries during COVID-19 Pandemic

By Muhammad Zahoor, Ihtisham Ul Haq

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Health Systems Approach to Ensure Quality and Safety Amid COVID-19 Pandemic in Pakistan

By Nousheen Akber Pradhan, Anam Shahil Feroz, Syed Mairajuddin Shah

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Imaging Patterns of Encephalopathy in Patients with COVID-19

By Kumail Khandwala, Fatima Mubarak, Muhammad Nadeem Ahmad

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A Single-centre Study of COVID-19 Antibody

By Sidra Ghazanfer, Hasan Osman Mahmood

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Association of Blood Groups with the Severity and Outcome of COVID-19 Infection in Children

By Attia Bari, Aimen Ch, Sidra Hareem, Iqbal Bano, Junaid Rashid, Masood Sadiq

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Prospective Effects of Covid-19 on Children: Probable Complications and Interventions

By Naeem Aslam Chughtai

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New Insight for Kidney Biopsy Series in Cases with COVID-19-related Acute Kidney Injury

By İlker Kaya

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