Journal of College of Physicians and Surgeons Pakistan (JCPSP), is the prestigious, peer reviewed monthly biomedical journal of the country published regularly since 1991. College of Physicians and Surgeons Pakistan is the parent body of this Journal.


The College of Physicians and Surgeons of Pakistan (CPSP) is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide credits to educational activities.

CPSP designates '3 AMA PRA Category 1 Credits' for review of the manuscript of an original study.


Latest Articles
Volume 29 | Issue 4 | April 2019
The Art of Healing – Core Values and Goals of Medicine, Nursing and Healthcare

By Muhammad Jawad Hashim

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Small-Dose Ropivacaine Hydrochloride with Fentanyl versus Large-Dose of Ropivacaine Hydrochloride for Cesarean Section

By Jinwen Huang, Xia Liu, Shaoli Ding, Lei Zhu, Wenjun Yan

Objective: To compare the effect of small-dose ropivacaine hydrochloride combined with fentanyl versus large-dose of ropivacaine hydrochloride for cesarean section. Study Design: Experimental study. Place and Duration of Study: Department of Anesthesiology, Gansu People's Hospital, China, fr...

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Diffusion-Weighted Magnetic Resonance Imaging in Assessment of Primary Liver Cancer after HIFU Treatment

By Sheng Li, Sili Shi, Aiping Li, Huihui Liu, Lili Cai

Objective: To determine the feasibility and role of diffusion-weighted magnetic resonance imaging (DWI) in the assessment of high-intensity focused ultrasound (HIFU) for the treatment of primary liver cancer. Study Design: An observational study. Place and Duration of Study: Department of Radiolo...

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Influence of Obesity Surgery on Restless Leg Syndrome

By Sabri Ozdas, Ramazan Ilyas Oner

Objective: To investigate whether restless leg syndrome (RLS) symptoms improved and treatment requirement decreased through weight loss on postoperative follow-ups of the patients who underwent laparoscopic sleave gastrectomy (LSG) due to obesity and who were started medical therapy due to RLS. S...

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Laparoscopic Surgery Combined with GnRH Agonist in Endometriosis

By Yu Yang, Weidong Zhu, Shuqiu Chen, Guangyuan Zhang, Ming Chen, Yuhong Zhuang

Objective: To determine the efficacy of laparoscopic surgery combined with GnRH agonist (GnRH-a) in treating infertile patients with endometriosis (EMs), and analyze its effect on the levels of serum hormones and inflammatory factors of the patients. Study Design: An experimental study. Place an...

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Entecavir and Low Genetic Barrier Antiviral Agents for Hepatocellular Carcinoma in Hepatitis B Viral Cirrhosis: Propensity Score Matching

By Tao Li, Yundong Qu, Yan Wang, Chunlei Lin, Baohua Yang, Lei Wang

Objective: To compare the reduction of hepatocellular carcinoma (HCC) risk between long-term treatment of entecavir and low genetic barrier antiviral agents in hepatitis B virus (HBV)-related cirrhotic patients. Study Design: An observational study. Place and Duration of Study: Department of Infe...

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Comparative Effects of Monosialoganglioside versus Citicoline on Apoptotic Factor, Neurological Function and Oxidative Stress in Newborns with Hypoxic-Ischemic Encephalopathy

By Shi-Peng Liang, Qian Chen, Yi-Bing Cheng, Ying-Ying Xue, Hai-Jun Wang

Objective: To determine the comparative effect of monosialoganglioside versus citicoline on the content changes of serum apoptotic factors (PDCD5, sFas and sFasL), neurological function indices (BDNF, NSE, S100-β and NGF) and oxidative stress indices (SOD, MDA and GSH-PX) in newborns with hyp...

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Clinical Characteristics of Patients on Long-term Hemodialysis

By Amna Hamid, Murtaza F. Dhrolia, Ruqayya Qureshi, Salman Imtiaz, Aasim Ahmad

Objective: To study the clinical characteristics of patients on hemodialysis for more than ten years in order to highlight the modifiable factors that may improve survival in low socioeconomic status. Study Design: Observational cross-sectional study. Place and Duration of Study: Department of Ne...

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Glucose Tolerance versus HbA1c Results as Depictive of Gestational Diabetes Mellitus

By Sikandar Hayat Khan, Robina Manzoor, Aasyia Hanif Baig, Farah Sobia, Nadeem Fazal, Najmusaqib Khan Niazi

Objective: To evaluate glucose tolerance patterns in pregnant ladies undergoing 2-hour oral glucose tolerance test (OGTT) for comparing fasting, 1-hour, 2-hour post-glucose load results, HbA1c, sum of all glucose readings with and without gestational diabetes mellitus (GDM) using International Ass...

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Differences of HBME-1 Expression in Thyroid Follicular Adenoma and Follicular Thyroid Carcinoma by Ultrasound-Guided Fine-Needle Aspiration Biopsy

By Junsong Wang, Li Xu, Xiaosen Xu, Xin Wang

Objective: To investigate the differences in human bone marrow endothelial cell marker 1 (HBME-1) expression in thyroid follicular adenoma (FA) and follicular thyroid carcinoma (FTC) by ultrasound-guided fine-needle aspiration biopsy. Study Design: An observational study. Place and Duration of St...

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Traditional versus Percutaneous Transforaminal Endoforaminal Discectomy Effect on the Nervous System Function and Serum LEK, GFAP and PGE-2 in Patients with Senile Lumbar Spinal Stenosis

By Hejun Chen, Junlian Xue, Xinjiang Wu

Objective: To compare the influence of percutaneous transforaminal endoscopic discectomy (PTED) and traditional operation on the nervous system function and the serum leu-enkephalin (LEK), glial fibrillary acidic protein (GFAP) and prostaglandin E-2 (PGE-2) in patients with senile lumbar spinal st...

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Montelukast and Budesonide for Childhood Cough Variant Asthma

By Wu Sun, Hai-Yan Liu

Objective: To determine the effects of combined treatment of montelukast and budesonide on young children with cough variant asthma, and their serum inflammatory factors of serum hypersensitive c-reactive protein (hs-CRP), tumour necrosis factor-α (TNF-α), interleukin-6 (IL-6) and pulm...

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Prevalence of Suicide Ideation and its Relationship with Depression among Transgender Population

By Rao Azeem, Usama Bin Zubair, Aneza Jalil, Asif Kamal, Asad Nizami, Fareed Minhas

Objective: To record the prevalence of suicidal ideation in the transgender population and assess the relationship of depression with the suicidal ideation. Study Design: Cross-sectional study. Methodology: The study group comprised of 156 transgender people of Rawalpindi and Islamabad. Suicidal ...

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Detection Rate of Thyroid Papillary Micro-carcinoma in Multinodular Goiter Surgery

By Bahri Ozer, Mustafa Sit, Gulali Aktas, Fatih Keyif, Ferdi Bolat, Hayri Erkol

Objective: To determine the frequency of papillary thyroid micro-carcinoma (PTMC) in multinodular goiter (MNG) surgery, as well as in opposite thyroid lobule of the dominant nodule. Study Design: Descriptive study. Place and Duration of Study: General Surgery Department, Abant Izzet Baysal Univer...

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Epidemiology and Treatment Outcomes of Sinonasal Tumors: A Single Institute's Experience in Pakistan

By Wajiha Anjum, Rab Nawaz Maken, Hasan Nisar, Ismat Fatima, Misbah Masood, Abu Baker Shahid

Objective: To find the epidemiology and risk factors of sinonasal tumors and treatment outcomes in squamous cell carcinoma. Study Design: An observational study. Place and Duration of Study: The Institute of Nuclear Medicine and Oncology Lahore (INMOL), Lahore, from May 2016 to March 2017. Meth...

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Impact of Prostate Specific Antigen Level on Oncological Outcomes after Open Radical Prostatectomy

By Mustafa Sungur, Selahattin Caliskan

Objective: To compare the impact of prostate specific antigen (PSA) on oncological outcomes in the patients with 4-10 and 10.01-20 ng/ml PSA level. Study Design: Retrospective comparative study. Place and Duration of Study: Hitit University, Çorum Erol Olçok Training and Research Ho...

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Self and Peer Assessment of Teachers' Attitude towards Teaching

By Ambreen Ansar, Robina Mushtaq Rizvi, Afsah Hussain, Ameera Nawaz, Abeera Zafar, Ammara Fayyaz

Objective: To appraise the attitude of the teachers towards teaching and the factors affecting their attitudes, and compare self-assessed attitudes of the medical teachers with teachers in social sciences. Study Design: Cross-sectional descriptive study. Place and Duration of Study: Wah Medical C...

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Conventional versus Minimally Invasive Vein Harvesting: A Clinical Audit of Wound Dehiscence Complications

By See Woan Shiang, Simon Jerome Vendargon, Syed Rasul Bin Ghouse Syed Hamid

Objective: To determine the wound complications post coronary artery bypass graft surgery (CABG) by conventional vein harvest technique (CVH) and minimally invasive vein harvest technique (MIVH) in Hospital Sultanah Aminah Johor Bahru, Malaysia. Study Design: Clinical audit report. Place and Dur...

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Chryseobacterium Indologenes as a Novel Cause of Bacteremia in a Neonate

By Irfan Ali Mirza, Ayesha Khalid, Fatima Hameed, Anam Imtiaz, Ambar Ashfaq, Anam Tariq

Chryseobacterium indologenes is a rare human pathogen. It is an emerging species, least frequently reported from pediatric age group and known to cause pneumonia, bacteremia, and meningitis. The inherent resistant of one of the species to commonly prescribed broad-spectrum antibiotics makes it for...

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Sequential Optic Neuritis: A Neuromyelitis Optica Spectrum Disorder

By Mehtab Alam, Mian Ayaz ul Haq, Asif Iqbal, Kaleem Ullah, Danish Nabi

Neuromyelitis optica spectrum disorder (NMOSD) is an autoimmune relapsing demyelinating disorder which often leads to severe disability typically targeting spinal cord, optic nerves, and brainstem. Around 75% of NMOSD patients have serum immunoglobulin-G (IgG) autoantibodies to the aquaporin-4 cha...

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Hypohydrotic Ectodermal Dysplasia in an Indian Family

By Anish A. Gupta, Swati S Gotmare, Megha Jain, Treville Pereira, Pooja Khare

Hereditary ectodermal dysplasia (HED) is a rare genetic disorder chiefly affecting ectodermally derived structures including hair, nails, sweat glands etc. with pathognomic manifestations such as hypotrichosis, hypohidrosis, and hypodontia. Hypohidrotic ectodermal dysplaisa, being the most frequen...

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A Novel Complication Following Retrograde Intrarenal Surgery: Retroperitoneal Hematoma

By Berat Cem Ozgur, Musa Ekici

Retrograde intrarenal surgery (RIRS) is an efficient method for kidney stones with low complication rates. Reported here is an unusual complication of this surgery; a retroperitoneal hematoma 8x7.5x5 cm in dimension in a 40-year female, which was completely resolved by conservative treatment. This...

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Oxidizing Effect of Ozonated-Water on Microbial Balance in the Oral Ecosystem

By Fathilah Abdul Razak, Md. Yusoff Musa, Husham Amra Mahmod Abusin, Nosizana Mohd. Salleh

Application of ozone is recommended for sterilisation in dental procedures. This study explored the antimicrobial effect of 0.1 ppm ozonated-water on selected common oral commensals. Based on deviation of their growth curves pattern upon ozone treatment, the inhibitory effect of ozone was determin...

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Clinical and Demographic Features of 76 Children with Autism Spectrum Disorders at a Centre in Pakistan

By Ghazal Nadeem, Aleena Bibi, Bushra Suhaib, Suhaib Ahmed, Suhaib Ahmed, Salman Ali

In this cross-sectional study, 76 consecutive children with autism spectrum disorder (ASD) were studied for the clinical and demographic parameters at Autism Resource Centre in Pakistan. The median age at first consultation was 30 months, 36 months at diagnosis, and 42 months at referral to a spec...

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Effect of Astragalus Polysaccharide on the Expression of VEGF and EGFR in Mice with Lewis Transplantable Lung Cancer

By Lichun Zhao, Yute Zhong, Jie Liang, Hongwei Gao, Nong Tang

The aim of this study was to determine the effect of Astragalus polysaccharide (APS) on the expression of vascular endothelial growth factor (VEGF) and epidermal growth factor receptor (EGFR) in mice with Lewis transplantable lung cancer. It was an experimental study carried out from June 2017 to ...

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Response to a Case Report titled: Anaesthetic Management of a Patient with Left Ventricular Non-Compaction Undergoing Laparotomy

By Faraz Shafiq, Muhammad Irfan Ul Haq, Anwar ul Huda

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Cutaneous Leishmaniasis caused by L. Infantum

By Arfan ul Bari, Nazma Habib Khan

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Rare Case of Pheochromocytoma in a Young Female

By Mohammad Masood Ur Rauf Hiraj Khan, Zia Hashmi, Ammarah Ghafoor

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Preventive Effect of Somatostatin on Pancreatitis and Hyperamylasemia after Therapeutic ERCP

By Shouhe Zhao, Junhua Yu

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Special Issue

Special Supplement 3 | Volume 28 | September 2018
Anaesthetic Management of a Patient with Left Ventricular Non-Compaction Undergoing Laparotomy

By Anwar ul Huda, Tauseef Ahmed

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Senning Procedure for Transposition of the Great Arteries in a Patient with Situs Inversus Totalis and Dextrocardia

By Iqbal Hussain Pathan, Sohail Khan Bangash, Saad Bader Zaki, Abdul Sattar Sheikh

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Patent Ductus Arteriosus with Infective Vegetations in Grandmultipara

By Ayesha Siddiqa, Nasira Sohail

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Large Aneurysm in Renal Angiomyolipoma

By Ateeque Ahmed Khan, Samiya Saquib, Rabia Hafeez, Sarosh Kadri

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MRI Appearances of Colitis Cystica Profunda: A Rare Benign Mimicker of Colorectal Malignancy

By Laiba Masood, Sana Sayeed, Maryam Asghar

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Massive Osteolysis in Distal Shaft of Humerus: A Case Report on Vanishing Bone Disease

By Sana Noman, Seema Faiz, Sohail Ahmed Khan, Amjad Sattar

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Acrophobia in a Young Girl with Parathyroid Hormone Resistance (Pseudohypoparathyroidism)

By Mehwish Gilani, Asif Ali Memon, Naveed Asif, Nida Basharat

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Thiamine Responsive Megaloblastic Anaemia, Diabetes Mellitus and Sensorineural Hearing Loss in a Child

By Ayesha Khurshid, Sarah Fatima, Chaudhry Altaf, Hamid Saeed Malik, Zunera Sajjad, Muhammad Tahir Khadim

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An Unusual Presentation of Langerhans Cell Histiocytosis

By Usama Rehman, Zafar Ali, Nadira Mamoon

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Invasive Community Acquired Methicillin-Resistant Staphylococcal Aureus (CA-MRSA) Infections in Children

By Muhammad Khalid, Samina Junejo, Fatima Mir

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Endovascular Aortic Repair for Thoracic Aortic Injuries

By Omer Ehsan, Usama Khalid Choudry, Atif Rana, Zahid Amin Khan

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Cerebral Abscess caused by Novel Species: Streptococcus Pluranimalium

By Abeera Ahmed, Gohar Zaman, Adeel Gardezi, Luqman Satti, Nargis Sabir, Aliya Haleem

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Management of Obstructive Sleep Apnea Syndrome Associated with Severe Micrognathia

By Muhammad Nazir Khan, Muhamamd Adil Asim, Irfan Shah

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Multidisciplinary Approach for Management of a Patient with Oral Mucosal Malignant Melanoma

By Prashanti Eachempati, Himanshi Aggarwal, Vidya Kamalaksh Shenoy, Mohan Baliga

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Proximal Tibial Osteochondroma Leading to Chronic Compartment Syndrome

By Jitendra Wadhwani, Sumedha Vashishth, Ramchander Siwach, Rajesh Rohilla

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Mabry Syndrome in a Child of South Asian Descent

By Amir Humza Sohail, Muhammad Younus Khan Durrani, Shahnaz Hamid Ibrahim, Khadija Nuzhat Humayun

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Hereditary Hemorrhagic Telangiectasia – Early Childhood Presentation with Hepatic Failure

By Syeda Shaheera Hashmi, Nighat Haider, Munir Iqbal Malik

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Enzyme Replacement Therapy in Hypophosphatasia

By S. Ahmet Uçaktürk, Selin Elmaogullari, Sevim Ünal, Deniz Gönülal, Eda Mengen

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Hybrid Lesion of Congenital Cystic Adenomatoid Malformation and Bronchopulmonary Sequestration

By Arshad Khushdil, Raazia Nawaz, Asma Razzaq, Naveed Ahmed

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Hybrid Lesion: Extralobar Sequestration with Cystic Adenomatoid Malformation – Misdiagnosed as Pulmonary Tuberculosis

By Fatima Naumeri, Muhammad Nadeem Sajjad

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Single Bilateral Undivided TRAM Flap for a Bilateral Breasts Reconstruction Including Intermammary Presternal Skin Defect Coverage

By Junaid Ahmad, Roomana Akhlaque, Moazzam Nazeer Tarar

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Effects of Combined Aerobic and Virtual Reality-Based Cognitive Training on 76 Years Old Diabetic Male with Mild Cognitive Impairment

By Raana Ali Mirza, Irum Yaqoob

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A Case Study on the Effectiveness of Cognitive and Behavioural Approaches for Diabetic Patient with Cardiac Disease

By Asiya Khalid, Mahwesh Arooj Naz

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Gunshot Injury of Head and Neck Region with an Atypical Bullet Trajectory: The Importance of Whole Body Computed Tomography Scan

By Yusuf Velioglu, Ahmet Yuksel, Baris Durgun

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Diagnosis and Treatment of Paratesticular Adenomatoid Tumors

By Ahmet Urkmez, Serkan Akan, Emrah Ozsoy, Aytac Sahin, Orhan Koca, Metin Ishak Ozturk

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A Case of Multiple Myeloma with Triple Herpes Virus Infections

By Misbah Noor, Saifullah Khan Niazi, Fatima Sana, Syed Kamran Mahmood

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HIV Negative Penile Kaposi's Sarcoma in Circumcised Men

By Ahmet Urkmez, Serkan Akan, Emrah Ozsoy

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