Impact Factor 1.0
Volume 34, 12 Issues, 2024

Journal of College of Physicians and Surgeons Pakistan (JCPSP), is an open access, peer reviewed monthly biomedical journal of the country published regularly since 1991. College of Physicians and Surgeons Pakistan is the parent body of this Journal.


The College of Physicians and Surgeons of Pakistan (CPSP) is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide credits to educational activities.

CPSP designates '3 AMA PRA Category 1 Credits' for review of the manuscript of an original study.


Important Announcement for Authors

"A companion journal of JCPSP (the official journal of CPSP) has been launched by the name of JCPSP Case Reports. Submission of Case Reports is now open."
Please visit https://jcpspcr.pk/.

Latest Articles
Volume 34 | Issue 4 | April 2024
Need for Nation-wide Regulatory Laws to Govern Privacy and Genomic Data in Healthcare

By Sikandar Hayat Khan


Treatment for Resistant Hypertension Under the Guidance of Pharmacogenomics: A Randomised Controlled Open-Label Trial

By Ai Wang, Muisha Bienvenue Mbikyo, Junzhe Zhang, Nan Cui, Zhao Li

ABSTRACT Objective: To evaluate the efficacy and safety of pharmacogenomics (PGx)-guided treatment in individuals with resistant hypertension (RH). Study Design: Randomised controlled open-label study. Place and Duration of the Study: Department of Cardiology, The First Hospital of China Medical Un...

Download PDF Read Full Article

Evaluation of Postoperative Pain after Using Dexamethasone Intracanal Rinse in Irreversible Pulpitis

By Iqra Dildar, Amna Moghal, Anam Mirza, Muhammad Adil Zaheer, Mariam Raza Mallick, Sidra Munir

ABSTRACT Objective: To evaluate the efficacy of dexamethasone as a final intracanal rinse in relieving postoperative pain of teeth with symptomatic irreversible pulpitis. Study Design: Randomised controlled trial. Place and Duration of the Study: Department of Operative Dentistry, PIMS, Islamabad, P...


SUVmax as Predictor of Metastatic Disease on 18F-FDG PET-CT in Hepatocellular Carcinoma

By Wardah Ashfaq, Khurram Rehman, Abubaker Shahid, Muhammad Numair Younis

ABSTRACT Objective: To ascertain the utility of maximum standardised uptake value (SUVmax) in 18F-FDG PET-CT in predicting metastatic disease burden in hepatocellular carcinoma (HCC) patients. Study Design: Descriptive study. Place and Duration of the Study: Department of Nuclear Medicine and P...

Download PDF Read Full Article

IVIM and DCE-MRI in Predicting Phenotypic Subtypes and Nottingham Prognostic Index of Breast Cancer

By Zhanguo Sun, Zhe Zhou, Lei Wang, Laimin Zhu, Yueqin Chen, Qiaolu Liu

ABSTRACT Objective: To explore the value of intravoxel incoherent motion (IVIM) and dynamic contrast enhanced MRI (DCE-MRI) for predicting phenotypic subtypes and Nottingham prognostic index (NPI) of breast cancer. Study Design: Descriptive study. Place and Duration of the Study: Department of Radio...

Download PDF Read Full Article

Analysing Crime Scene Data, Medical Records and Forensic Information to Determine the Causes of Suicides

By Ali Ramazan Benli, Erhan Simsek

ABSTRACT Objective: To analyse crime scene data, medical records, and forensic information to unveil insights into the causes and traits of suicides. Study Design: Descriptive study. Place and Duration of the Study: Department of Family Medicine, Kayseri City Hospital, Kayseri, Turkiy...

Download PDF Read Full Article

Risk Factors and Risk Assessment for Post-Endoscopic Retrograde Cholangiopancreatography Pancreatitis

By Chengjin Zhao, Ting Dai, Junbo Qian, Zhenming Ge

ABSTRACT Objective: To analyse the pertinent risk factors associated with post-endoscopic retrograde cholangiopancreatography pancreatitis (PEP) and develop a predictive scoring system for assessing the risk of PEP in patients undergoing endoscopic retrograde cholangiopancreatography (ERCP) procedur...

Download PDF Read Full Article

Genotypic Frequency of Rh Cw Antigen in Blood Donors of Northern Pakistan

By Sarah Fatimah, Asad Mahmood Abbasi, Ali Abbasi, Nargis Sabir, Rozina Ghani, Rehan Ahmed Khan Lodhi

ABSTRACT Objective: To determine the genotypic frequency of Rh Cw antigen in blood donors of Northern Pakistan. Study Design: Descriptive cross-sectional study. Place and Duration of the Study: Department of Molecular Haematology, Armed Forces Institute of Transfusion (AFIT), Rawalpindi, Pakistan, ...


Impact of MLL::AF9 Gene Rearrangement on Survival of Acute Myeloid Leukaemia Patients: An Insight into Pakistani Population

By Muhammad Tariq, Sadaf Shahab, Javeria Rauf Saeed, Zeeshan Hussain, Uzma Zaidi, Tasneem Farzana, Sultan Ahmad

ABSTRACT Objective: To ascertain the frequency of the MLL::AF9 gene rearrangement and its association with survival in Pakistani patients suffering from acute myeloid leukaemia (AML). Study Design: Analytical study. Place and Duration of the Study: Department of Haematology, National Institute of ...

Download PDF Read Full Article

Effects of Novel Insulin Resistance Indices on Early Renal Functions in Donors

By Metin Yigman, Ahmet Emin Dogan

ABSTRACT Objective: To investigate the relationship between quickly calculable new insulin resistance (IR) indices used to evaluate IR in early kidney functions after donor nephrectomy. Study Design: Descriptive design. Place and Duration of the Study: Department of Urology, Ufuk University Faculty ...


The Relationship Between Composite Inflammatory Ratios and Complications of Massive Ischaemic Stroke

By Liqin Zheng, Zhijian Lin

ABSTRACT Objective: To investigate the relationship between complications of massive cerebral infarction (MCI) and composite inflammatory ratios. Study Design: A case-control study. Place and Duration of the Study: Department of Neurology, Affiliated Hospital of Putian University, Putian, China, fro...

Download PDF Read Full Article

Validation of a Predictive Model of Vaginal Birth after Caesarean Section in Pakistani Women

By Asra Bari, Riffat Jaleel, Shehla Arif

ABSTRACT Objective: To determine the frequency of successful trials of vaginal birth after Caesarean section (VBAC) using the Flamm and Geiger model. Study Design: Observational study. Place and Duration of the Study: Obstetrics and Gynaecology Unit II of Dr. Ruth K.M. Pfau Civil Hospital, Karachi, ...

Download PDF Read Full Article

Correlation Between the Clinicopathological Features of Papillary Thyroid Carcinoma Complicated with Hashimoto's Thyroiditis, BRAF V600E Gene Mutation, and RET Gene Rearrangement

By Min Xie, Zeng Xiang Xu, Min Dai, Yong Yun Zhu

ABSTRACT Objective: To analyse the expression of BRAF V600E protein and RET gene rearrangement in papillary thyroid carcinoma (PTC) combined with Hashimoto's thyroiditis (HT) and to explore its clinical and pathological significance. Study Design: Observational study. Place and Duration of the ...


Low HDL-C and the Risk of Hospitalisation in Children with COVID-19

By Nurhan Kasap, Onur Incealtin, Velat Celik, Mehmet Agirbasli

ABSTRACT Objective: To investigate high-density lipoprotein cholesterol (HDL-C) levels in children with COVID-19. Study Design: Descriptive study. Place and Duration of the Study: Goztepe Professor Suleyman Yalcin City Hospital, Istanbul, Turkiye, between 2020 and 2022. Methodology: The hospital da...

Download PDF Read Full Article

Predictive Ability of LRINEC Score for Lower Extremity Amputation in Moderate to Severe Diabetic Foot Infection

By Abdul Hameed, Shahid Mehmood Khan, Muhammad Tawab Khalil, Ahmed Tariq, Muhammad Fawad, Muhammad Ajmal Leghari

ABSTRACT Objective: To assess the predictive ability of the laboratory risk indicator for necrotising fasciitis (LRINEC) score for lower extremity amputation in patients with moderate to severe diabetic foot infection (DFI). Study Design: Observational study. Place and Duration of the Study: Depar...

Download PDF Read Full Article

Prophylactic Cranial Irradiation in Limited-Stage Small Cell Lung Cancer: A Meta-Analysis

By Cheng Chi, Congcong Wang, Liangliang Dong, Xiaoping Li, Lulu Xu

ABSTRACT The role of prophylactic cranial irradiation (PCI) in limited-stage small cell lung cancer (LS-SCLC) has been questioned in the era of magnetic resonance imaging (MRI). The purpose of this study was to re-evaluate the efficacy of PCI in patients with LS-SCLC. Three electronic databases were...

Download PDF Read Full Article

Relationship Between Heart Rate Variability Parameters and Short-Term Prognosis of Patients with Acute Myocardial Infarction

By Chun-Mei Wang, Tao-Tao Su, Yang Yue, Wei-Xing Han

ABSTRACT Objective: To determine the link between heart rate variability (HRV) and short-term adverse outcomes (re-hospitalisation or death due to cardiac arrhythmia, recurrent myocardial infarction, heart failure, all-cause death) in acute myocardial infarction (AMI). Study Design: A descriptive s...

Download PDF Read Full Article

Management of Chronic Osteomyelitis and Antibiotic Stewardship; An Effort to Delay the Post-Antibiotic Era

By Abeera Ahmed, Ahmed Mushtaq, Irfan Ali Mirza, Fatima Sana, Syed Rehan Asghar Naqvi

ABSTRACT Objective: To develop an effective antimicrobial strategy for the management of chronic osteomyelitis. Study Design: Observational study. Place and Duration of the Study: Departments of Microbiology and Orthopaedics, Combined Military Hospital Malir, Karachi, Pakistan, from January 2021 to ...

Download PDF Read Full Article

Acute Graft versus Host Disease in Beta Thalassemia Patients Following Allogeneic Haematopoietic Stem Cell Transplantation

By Nabila Rafique, Asghar Ali, Tariq Ghaffor, Tariq Azam Khattak, Muhammad Bilal Asghar, Qammar-un-Nisa Chaudhry

ABSTRACT Objective: To analyse the frequency, risk factors, and clinical symptoms of acute graft-versus-host disease (aGvHD) in patients with beta-thalassemia major after allogeneic haematopoietic stem cell transplantation (HSCT). Study Design: Descriptive study. Place and Duration of the Study: De...


Are We Providing Enough Information to the Pathologists? An Audit of Filling of Histopathology Request Forms for Surgically Resected Tumours

By Mishaal Shan Siddiqui, Suresh Kumar, Dinesh Kumar, Saad Khalid, Wardah Hassan, Mahima Khatri

ABSTRACT Objective: To analyse quantitatively the adequacy of demographics of clinical information and highlight specific areas of neglect, by assessing the adequacy of filling out histopathology request forms. Study Design: Clinical Audit. Place and Duration of the Study: Department of Pathology, D...


Da Vinci Robotic Surgical System: Early Experience from Pakistan

By Harris Hassan Qureshi, Rehan Mohsin, Naveed Ahmed Mahar, Riaz Ahmed Laghari, Mushtaq Hussain, Altaf Hashmi

ABSTRACT Objective: To determine the outcomes of robotic surgeries using the Da Vinci robotic surgical system (DVSS) at Pakistan’s largest urological tertiary healthcare system. Study Design: Descriptive study. Place and Duration of the Study: Department of Minimally Invasive and Robotic Surge...

Download PDF Read Full Article

Translating and Validating PRISMA-7 Questionnaire in Urdu: A Screening Tool to Identify Frail Individuals

By Umema Zafar, Mian Saad Ahmed, Nimra Zafar, Faisal Hassan

ABSTRACT Frailty is a condition in which the affected individual is more prone to both external and internal stressors and has a higher risk of succumbing to chronic diseases. The aim of this research was to translate and validate the PRISMA-7 questionnaire in the Urdu language. This is a validation...


Performance Evaluation of SARS-CoV-2 Rapid Antigen Test Among Symptomatic and Asymptomatic Patients in the Emergency Department of a Tertiary Care Hospital

By Nayab Afzal, Shabnum Dildar, Razia Aijaz

ABSTRACT The aim of this study was to evaluate the diagnostic performance of the SARS-CoV-2 rapid antigen test (RAT) for the diagnosis of COVID-19 among symptomatic and asymptomatic patients. This retrospective study was done from 15th November 2021 to 15th December 2021, at National Medical Centre,...


Understanding the Impact of Climate Change on Oral Health in Lower
Middle-Income Countries

By Wajiha Qamar, Mehran Qayum


Rare Urinary Tract Infections in Immunosuppressed Patients: Not Just Anti-Infectives

By Donguil Liang, Xiaodong Li


Traditional Teaching and Learning Methodologies: Innovations Needed

By Mehwash Kashif, Maliha Mohsin


Identifying Medical Students in Difficulty Using Integration of Programmatic Assessment and Real-Time Evaluation Framework

By Khadija Farrukh Warraich, Shehla Baqai


Low Dose Sorafenib in Gastric Gastrointestinal Stromal Tumour with PDGFRA p.1843-D846 Deletion in an 88-Year-Old Male

By Asif Husain Osmani