5-Year Impact Factor: 0.9
Volume 35, 12 Issues, 2025

Journal of College of Physicians and Surgeons Pakistan (JCPSP), is an open access, peer reviewed monthly biomedical journal of the country published regularly since 1991. College of Physicians and Surgeons Pakistan is the parent body of this Journal.


The College of Physicians and Surgeons of Pakistan (CPSP) is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide credits to educational activities.

CPSP designates '3 AMA PRA Category 1 Credits' for review of the manuscript of an original study.


Important Announcement for Trainees

"A companion journal of JCPSP (the official journal of CPSP) has been launched by the name of JCPSP Postgraduate (JCPSP PG). Submissions to JCPSP PG will be open from March 01, 2025"
For more details, Please visit https://jcpsppg.pk/.

Latest Articles
Volume 35 | Issue 7 | July 2025
CPSP’s Drive Towards Innovation – Advancing Assessment, Education, and Engagement

By Khalid Masud Gondal


Testosterone to Oestradiol Ratio: A Significant Indicator for Prediction of Coronary Artery Disease in Males

By Hafsa Aziz, Muhammad Anwar, Muhammad Qaiser Alam Khan, Muhammad Younas, Zujaja Hina Haroon, Uzma Naeem

ABSTRACT Objective: To determine the association of serum testosterone / oestradiol ratio (T/E2) with coronary artery disease (CAD) in males. Study Design: A comparative cross-sectional study. Place and Duration of the Study: Department of Chemical Pathology, Armed Forces Institute of Pathology, in ...


Predictive Value of the Naples Prognostic Score on New-Onset Atrial Fibrillation in ST-Segment Elevation Myocardial Infarction Following Primary Percutaneous Coronary Intervention

By Yang Ling, Chen Liang, Renjie Wu, Jinfeng Wang

ABSTRACT Objective: To investigate the connection between Naples prognostic score (NPS) and new-onset atrial fibrillation (NOAF) in ST- segment elevation myocardial infarction (STEMI) cases following revascularisation. Study Design: An observational study. Place and Duration of the Study: Department...


MMP-8, IL-6, and IL-1β: The Most Promising Salivary Biomarkers for Early Diagnosis of Periodontitis

By Maria Ali, Yasmeen Taj, Farzeen Tanwir, Shaista Bakhat, Syed Adeel Ahmed

abstract Objective: To evaluate the salivary levels of MMP-8, IL-1β, and IL-6 in patients with periodontitis and healthy controls, and to assess the association between these biomarkers and clinical parameters of periodontal disease. Study Design: A case-control study. Place and Duration of the...

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Comparison of Postoperative Pain Using Endo-Activator Vs. Conventional Irrigation in Symptomatic Periapical Periodontitis: A Randomised Controlled Trial

By Soha Pirzado, Syed Yawar Ali Abidi, Maham Muneeb Lone, Samira Adnan, Isma Sajjad, Jamshed Ahmed

ABSTRACT Objective: To compare the frequency of pain after using endo-activator and conventional irrigation in patients presenting with symptomatic periapical periodontitis following endodontic treatment by means of a visual analogue scale (VAS). Study Design: Randomised clinical trial. Place and D...

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Dental Caries in Patients with Fluorosis among Local Population of Hyderabad

By Feroze Ali Kalhoro, Saima Yousif, Muhammad Muhtassim, Sarang Suresh, Priya Rani, Naresh Kumar

ABSTRACT Objective: To assess the frequency of dental caries among individuals with dental fluorosis and to examine the relationship between fluorosis severity with the Thystrup-Fejerskov (TF) index and caries experience with the decayed, missing, and filled teeth (DMFT) index. Study Design: A cross...

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Gender-Based Dimorphism of Maxillary and Sphenoid Air Sinuses Via 3D Volumetric Segmentation of CBCT in a Sample of Egyptians

By Ehab Samir Ali Abuelola, Ola Mohamed Rehan, Hany Omar

ABSTRACT Objective: To determine gender in forensic odontology by volume calculation of maxillary and sphenoid sinuses via three-dimensional (3D) semi-automatic segmentation using cone beam computed tomography (CBCT) datasets in a sample of Egyptians. Study Design: A cross-sectional descri...

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Outcome of Carpal Tunnel Release with Longitudinal Mini Incision: A Prospective Cohort

By Muhammad Ahsan Sulaiman, Muhammad Ahmad Ghazni, Marij Zahid, Muhammad Omer Farooq, Muhammad Saad Iqbal, Pervaiz Mehmood Hashmi

ABSTRACT Objective: To determine the outcome of longitudinal mini incision (1.5 cm) for carpal tunnel release (CTR), using the Boston carpal tunnel questionnaire (BCTQ) to measure symptomatic relief, functional recovery, and postoperative complications. Study Design: Experimental study. Place and Du...


Comparative Study of the Protective Effects of Alpha-Lipoic Acid and Alpha-Tocopherol on Isoniazid-Induced Hepatitis in Mice

By Ikram Ullah Khan, Shabana Ali, Arooj Shahid, Muhammad Rafay Rasheed, Malik Sikandar Mehmood, Barkat Ullah Khan

ABSTRACT Objective: To assess the preventive role of alpha-tocopherol (vitamin E) and alpha-lipoic acid (ALA) in isoniazid-induced hepatitis. Study Design: Experimental study. Place and Duration of the Study: Department of Pharmacology, Army Medical College, National University of Medical Sciences...


Comparison of Serum Prolidase Activity in Smokers and Non-Smokers

By Tahire Betul Kor, Basri Furkan Dagcioglu, Aygul Tikit, Salim Neselioglu

ABSTRACT Objective: To investigate the effect of smoking on serum prolidase enzyme activity and proline/hydroxyproline levels. Study Design: A case control study. Place and Duration of the Study: Department of Family Medicine, Ankara Bilkent City Hospital, Family Medicine, Ankara, Turkiye, from June...

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Antimicrobial Resistance Patterns in Pseudomonas Aeruginosa Isolated from Chronic Suppurative Otitis Media

By Sadaf Razzak, Muhammad Sohail, Fakhur Uddin, Muhammad Razzaq Dogar

ABSTRACT                   Objective: To investigate the frequency, antimicrobial susceptibility, and associated risk factors for Pseudomonas aeruginosa in chronic suppurative otitis media (CSOM) infections. S...

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Efficacy of Rituximab Combined with Glucocorticoid for Nephrotic Syndrome and the Impact on Renal Function, Coagulation Function, and Inflammatory Response

By Si Shi, Jie Zeng, Yang Liu, Bingquan Li

ABSTRACT Objective: To explore the efficacy of rituximab combined with glucocorticoid for nephrotic syndrome and the impact on renal function, coagulation function, and inflammatory response. Study Design: Observational study. Place and Duration of the Study: Department of Nephrology, Xianyang Cent...

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Safety and Efficacy of Low Molecular Weight Heparin Vs. Direct Oral Anticoagulants in Cancer-Associated Venous Thromboembolism

By Samar Minallah, Amer Rehman Farooqi, Kashif Sajjad, Zainab Shakeel, Manzoor Khan, Sajjad Ullah

ABSTRACT Objective: To compare the safety and efficacy of low molecular weight heparin (LMWH) and direct oral anticoagulants (DOACs) in treating venous thromboembolism (VTE) among cancer patients. Study Design: Descriptive study. Place and Duration of the Study: Department of General Medicine, Shauk...


Refeeding Syndrome in Children Aged 6 to 59 Months with Severe Acute Malnutrition

By Abdul Salam Memon, Muhammad Rafique, Amanullah Lail, Kulsoom Abdul sattar, Zainab Khalid, Malik Sohail Danish

ABSTRACT Objective: To assess the frequency and factors of refeeding syndrome in children aged 6 to 59 months with severe acute malnutrition (SAM). Study Design: Descriptive, cross-sectional study. Place and Duration of the Study: Department of Paediatric Medicine, Civil Hospital, Karachi, Pakistan,...


Incisional Hernia Repair: Meta-Analysis on Laparoscopic and Open Surgical Repair

By Rosario Vecchio, Serena Scilletta, Eva Intagliata

ABSTRACT Despite the benefits of laparoscopic surgery, routine laparoscopic treatment of incisional hernia remains controversial. The aim of this meta-analysis was to compare the outcomes after laparoscopic and open incisional hernia repair and to assess the advantages and limitations of these techn...


Balancing Benefits and Risks of the Use of Cage in Lumbar Spondylolisthesis Surgery: A Meta-Analysis

By Yunpeng Mao, Feng Yao, Chao Xu, Xinlin Wu, Yuhao Yang, Fuyong Zhang

ABSTRACT Lumbar spondylolisthesis is a prevalent spinal disorder for which the primary treatment approach involves surgical intervention, including reduction, decompression, internal fixation, and bone graft fusion. This systematic review evaluated and compared the clinical efficacy of posterior lum...


Team Objective Structured Bedside Assessment (TOSBA) in Paediatric Undergraduate Students

By Heena Rais, Azam Saeed Afzal, Amber Shamim Sultan, Farhana Zafar

ABSTRACT Objective: To develop a team objective structured bedside assessment (TOSBA) tool for assessing the paediatric undergraduate students’ clinical skills at the bedside. Study Design: A validation, cross-sectional study. Place and Duration of the Study: Department of Paediatrics, Ziauddi...


Effect of the COVID-19 Pandemic on Anaesthetic Workload at a Tertiary Care Hospital in Pakistan

By Aliya Ahmed, Azmeena Nizar, Gauhar Afshan

ABSTRACT Objective: To compare the anaesthetic workload during the COVID-19 pandemic with the workload immediately before and two years after the pandemic at a tertiary care hospital in Karachi, Pakistan. Study Design: Observational study. Place and Duration of the Study: The operating rooms of...

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Factors Influencing Glycaemic Control in Adolescents with Type I Diabetes: Cross-Sectional Analysis of Individual and Parental Factors

By Fozia Memon, Muzna Arif, Maryam Haider, Muhammad Farrukh Qazi, Imran Nisar, Khadija Nuzhat Humayun

ABSTRACT Objective: To identify modifiable risk factors that influence glycaemic control in Type I Diabetic adolescents. Study Design: A cross-sectional analytical study. Place and Duration of the Study: Outpatient clinics, Department of Paediatric, Endocrinology, and Child Health, The Aga Khan Uni...


Anti-MOG Antibody Associated Disorders in Pakistan

By Tahira Mohammad, Arsalan Ahmad, Tahir Aziz Ahmed

ABSTRACT Objective: To present clinicopathological features and treatment outcomes of patients who tested positive for anti-myelin oligodendrocyte glycoprotein (MOG) antibodies in the catchment Pakistani population. Study Design: Observational study. Place and Duration of the Study: Department of I...


Cost-Effectiveness of Bariatric Surgery for the Treatment of Obesity: A Cost-Utility Analysis at International Metabolic and Bariatric Centre

By Mushtaq Ahmad, Maria Alamgir, Waqar Ahmad, Mah Noor Dad Khan, Abdul Haseeb Sahibzada

ABSTRACT Objective: To determine the cost-effectiveness of bariatric surgery in comparison to conservative treatment options in managing obesity and its secondary complications. Study Design: A cross-sectional survey. Place and Duration of the Study: Department of Bariatric Surgery, I...


Intralesional Triamcinolone Alone Vs. Combined Platelet-Rich Plasma for Keloid Treatment

By Imtiaz Khan Afridi, Shah Fiaz, Aiman Wazir, Salma Noreen

ABSTRACT Objective: To compare the efficacy of intralesional triamcinolone acetonide alone versus its combination with platelet-rich plasma (PRP) in the treatment of keloids. Study Design: Quasi-experimental study. Place and Duration of the Study: Department of Dermatology, MTI-Hayatabad Medical Com...


Petri Dishes to PCR: Navigating the Transition from Traditional to Molecular Diagnostic Techniques in Microbiology

By Moiz Ahmed Khan

ABSTRACT Clinicians have always been concerned with the prompt and accurate diagnosis of infectious diseases. With the advent of modern technology, such as automated identification systems and molecular testing, traditional methods such as microscopy and culture, which have been useful for decades, ...


Correlation of HER2 Expression in Gastric Carcinoma with Clinicopathological Parameters in the Omani Population

By Asim Qureshi, Hana Al Julandana, Sara Al Barkhati, Ahmed Al Ghaithi, Asem Shalaby

ABSTRACT This retrospective study was conducted to determine the relation between human epidermal growth factor receptor 2 (HER2) expression and the clinicopathological and prognostic characteristics of gastric cancer (GC) patients treated at the Department of Pathology, College of Medicine and Heal...


Comparison of Pulmonary Index Score after Treatment with Salbutamol Through Nebulisers Vs. Metered–Dose Inhalers with Spacer Device for Treatment of Childhood Wheeze

By Arooj Khan, Shaista Azeem Khan, Syed Mohsin Ali Shah, Faizan Sadiq, Abdul Khaliq, Shahana Nisar

ABSTRACT The aim of this study was to compare the mean pulmonary index score after Salbutamol delivery through nebulisers and metered-dose inhalers with spacers for the treatment of wheezing in children aged between 6 and 24 months. This randomised controlled trial was conducted from September 2023 ...


Clinical Study of Computed Tomography Angiography for Acute Cerebral Infarction

By Juan Wu, Jinyan Chen, Di Ji


Treatment of Severe Diabetic Foot Ulcers and Progressive Gangrene

By Cailing He, Hong Yin, Shoubao Wang


Treatment of Ossification or Sclerosis of the Posterior Longitudinal Ligament of the Cervical Spine Using New Techniques

By Wendong Xie, Xiudong Liu, Chao Zhang


Surgical Treatment of Ischaemic Necrosis of the Second Metatarsal Head of the Right Foot: Part 1

By Yu Liu


Comment on Optimum Working Hours for College of Physicians and Surgeons Pakistan Fellowship Residents of General Medicine and General Surgery Disciplines

By Sidra Waqar Qureshi, Erum Anwar