5-Year Impact Factor: 0.9
Volume 35, 12 Issues, 2025
  Letter to the Editor     December 2025  

Ectopic Tooth in the Nasal Cavity Following Maxillary Ameloblastoma Resection

By Wanhong Liang

Affiliations

  1. Department of Critical Care Medicine, Zhuhai Hospital of Integrated of Traditional Chinese Medicine and Western Medicine, Zhuhai, China
doi: 10.29271/jcpsp.2025.12.1639

Sir,

Intranasal ectopic teeth (IET) are exceptionally rare, with an estimated prevalence of 0.1%-1% in the general population and a noted male predilection (60–70% of cases).1-5 The exact aetiology remains unclear; however, trauma, infection, and developmental disorders have been hypothesised as possible reasons. Notably, most cases lack identifiable causes.

A 25-year man presented with persistent right-sided nasal discharge and pain. He had previously undergone surgical excision of a right maxillary sinus cyst in 2012 for similar symptoms. In 2013, due to suspected recurrence of the cyst, he underwent a second maxillary sinus cyst excision. Pathological examination again confirmed a benign lesion. Persistent symptoms prompted him to seek surgical intervention again in 2014, when a pathological examination confirmed the diagnosis of ‌ameloblastoma‌. His postoperative recovery was uneventful, and  his  symptoms  resolved  completely.

Figure 1: CT images of the ectopic tooth. (A) Axial: CT scan shows the ectopic tooth (arrow). (B) Coronal: The ectopic tooth was located at the inferior  margin  of  the  maxillary  sinus.

Figure 2: (A) Endoscopic image of the ectopic tooth. (B) Specimen of the ectopic tooth.

In 2023, the patient returned with recurrent right-sided nasal discharge ‌accompanied by epistaxis. Nasal cavity examination revealed a white mass. Computed tomography (CT) scan confirmed the presence of ‌an ectopic tooth within the right nasal cavity‌ (Figure 1A and B). Nasal endoscopy revealed a ‌pearly white mass‌ extending from the nasal floor (Figure 2A). The patient subsequently underwent ‌endoscopic removal of the ectopic tooth under general anaesthesia‌ (Figure 2B). Intraoperative findings revealed the ‌absence of the right inferior turbinate‌ and a patent right maxillary sinus ostium. Within the sinus, ‌cystic tissue was found encapsulating the tooth‌. The nasopharynx appeared grossly normal. The surgeon performed ‌radiofrequency ablation‌ of the cystic tissue using a plasma knife probe, extracted the tooth, and obtained biopsy samples of the cystic tissue for pathological analysis. Pathological examination ‌showed no evidence of tumour recurrence‌. The ectopic tooth was likely a result of the patient's prior maxillary pathology. Postoperatively, the patient experienced ‌favourable mucosal healing without crusting‌. His symptoms resolved completely, and he reported ‌no dysaesthesia‌.

This case is the first reported instance of the ectopic tooth following surgical resection of maxillary sinus ameloblastoma, diverging from the previous literature, which primarily attri-buted nasal ectopia to congenital factors. Endoscopic removal, as the preferred treatment, effectively mitigates complications from nasal foreign bodies, aligning with the established surgical protocols. This rare case highlights long-term surgical  risks  and  supports  endoscopic  management.

COMPETING  INTEREST:
The  author  declared  no  conflict  of  interest.

AUTHOR’S CONTRIBUTION:
WL: Drafting, revision, editing, analysis, interpretation, and the final approval  of  the  manuscript  to  be  published.

REFERENCES

  1. Khanna S, Turner M. Ectopic tooth in the nose. N Engl J Med 2021; 385(23):e82. doi: 10.1056/NEJMicm2112363.
  2. Berberi A, Aoun G, Hjeij B, AboulHosn M, Al Assaad H, Azar E. Bilateral ectopic third molar in the maxillary sinuses associated with dentigerous cyst: A case report. Med Pharm Rep 2023; 96(2):221-4. doi: 10.15386/mpr-2072.
  3. Abdollahifakhim S, Mousaviagdas M. Ectopic molar with maxillary sinus drainage obstruction and oroantral fistula. Iran J Otorhinolaryngol 2013; 25(72):187-92.
  4. Raubaite R, Rakauskaite A, Sukyte-Raube D, Zaleckas L, Rauba D. An intranasal ectopic tooth in an adult. Cureus 2022; 14(4):e24410. doi: 10.7759/cureus.24410.
  5. AlMulhim A, AlMomen A, AlKhatib A. Ectopic intranasal canine tooth in a child: A rare case report and literature review. Int J Surg Case Rep 2019; 55:202-5. doi: 10.1016/ j.ijscr.2019.01.037.