5-Year Impact Factor: 0.9
Volume 35, 12 Issues, 2025

Journal of College of Physicians and Surgeons Pakistan (JCPSP), is an open access, peer reviewed monthly biomedical journal of the country published regularly since 1991. College of Physicians and Surgeons Pakistan is the parent body of this Journal.


The College of Physicians and Surgeons of Pakistan (CPSP) is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide credits to educational activities.

CPSP designates '3 AMA PRA Category 1 Credits' for review of the manuscript of an original study.


Latest Articles
Volume 35 | Issue 9 | September 2025
Haematological Malignancies in Pakistan: A Critical Gap in Cancer Registration Requiring Urgent Attention

By Sana Khurram, Muhammad Asif Qureshi


Postoperative Atrial Fibrillation Following Isolated Coronary Artery Bypass Grafting: Incidence, Predictors, and Clinical Outcomes

By Mehmet Rum, Halit Er, Fatmagul Yilmaz, Levent Ceylan, Bulend Ketenci

ABSTRACT Objective: To investigate the incidence of postoperative atrial fibrillation (POAF) in patients following isolated coronary artery bypass grafting (CABG), evaluate its impact on mortality and morbidity, and analyse demographic and comorbid variables associated with its onset. Study Design: ...

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Transcriptomic Analysis of Circular RNA as Potential Biomarkers in Diagnosing Atopic Dermatitis

By Xuesong Xiang, Chang Liu, Huihuang He, Wenhong Qiu, Kaiwen Guo

ABSTRACT Objective: To investigate the functional role of circular RNAs (circRNAs) in atopic dermatitis (AD) and discover potential biomarkers for improved diagnosis and treatment. Study Design: Descriptive analytical study. Place and Duration of the Study: Department of Immunology, School of Medici...

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Assessing the Efficacy of High-Intensity Focused Ultrasound for Uterine Fibroids Using Dynamic Contrast-Enhanced-Magnetic Resonance Imaging

By Meixian Wu, Junfeng Li, Lu Huang, Jieru Wei, Hui Qin, Wenhua Qin

ABSTRACT Objective: To evaluate the efficacy of high-intensity focused ultrasound (HIFU) the treatment of uterine fibroids using dynamic contrast-enhanced-magnetic resonance imaging (DCE-MRI). Study Design: Descriptive study. Place and Duration of the Study: Department of Radiology, Liuzhou Hospital...

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Video-Assisted Anal Fistula Treatment (VAAFT) for Complex Perianal Fistulae with Long-Term Follow-Up

By Muhammed Amir, Fareeha Farooqui, Sehrish Latif, Sohaib Khan, Amina Amin, Sibgha Aimon

ABSTRACT Objective: To evaluate the clinical outcomes of video-assisted anal fistula treatment (VAAFT) in patients with complex perianal fistulae, with particular focus on complications and recovery. Study Design: A non-randomised observational study. Place and Duration of the Study: Department of S...

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Comparative Analysis of Metabolic and Inflammatory Biomarker Profiles in Phenotypes of Metabolic Dysfunction-Associated Fatty Liver Disease

By Sumbal Nida, Dilshad Ahmed Khan, Muhammad Qaiser Alam Khan, Muhammad Amjad Pervez, Sultan Saleem, Nayyar Chaudhry

ABSTRACT Objective: To investigate the differences in metabolic and inflammatory biomarker profiles across three metabolic dysfunction-associated fatty liver disease (MAFLD) phenotypes. Study Design: A comparative observational study. Place and Duration of the Study: This study was conducted at Pak...

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Sigma Metrics as a Measure to Evaluate Internal Quality Control Performance in a Clinical Chemistry Laboratory

By Rukhsana Tumrani, Syeda Sabahat Haider Zaidi, Anum Iftikhar, Haniah Ahmad, Afsheen Nigar, Tahera Alam Kadir

ABSTRACT Objective: To determine the sigma metrics of biochemical parameters in a clinical chemistry laboratory and to evaluate their individual performance on the sigma scale using the quality goal index (QGI) ratio. Study Design: Retrospective cross-sectional study. Place and Duration of the Study...

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Comparative Effectiveness of Gabapentin and Pregabalin Combination Therapy in Postherpetic Neuralgia: A Single-Masked Randomised Controlled Trial

By Lu Tao, Die Yin, Jun Xie

ABSTRACT Objective: To compare the efficacy of gabapentin combined with pregabalin in postherpetic neuralgia (PHN) attenuation, focusing on patient-reported outcomes and inflammatory cytokine reduction. Study Design: Single-blinded randomised controlled trial. Place and Duration of the Study: Depar...

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Postoperative CA-125 as a Prognostic Marker for Overall Survival in Ovarian Cancer

By Ahmet Burak Agaoglu, Ferhat Ekinci, Atike Pinar Erdogan, Mustafa Sahbazlar, Emine Turkmen

ABSTRACT Objective: To investigate the association between postoperative CA-125 levels and overall survival (OS) in patients with ovarian cancer, assessing its potential role as a prognostic biomarker. Study Design: Observational study. Place and Duration of the Study: Department of Medical Oncology...

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Causal Associations Between Socioeconomic Status and Corneal Diseases: A Multivariate Mendelian Randomisation Study

By Jianqin Yu, Rongrong Jing, Lusheng Wang

ABSTRACT Objective: To investigate the causal relationship between socioeconomic status (SES) and corneal diseases. Study Design: Two-sample Mendelian randomisation (MR) analysis. Place and Duration of the Study: Department of Pharmacy, Eye Hospital, Wenzhou Medical University, Wenzhou, China, betwe...

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Effects of Controlled Hypotension on Postoperative Cognitive Outcomes Following Nasal Surgery

By Murat Kaykac, Selcuk Kayir, Guvenc Dogan, Meryem Ecem Bebek, Muhammed Talha Kiratli, Ozgur Yagan

ABSTRACT Objective: To assess the impact of varying levels of controlled hypotension on cerebral oxygenation and examine their association with postoperative delirium and cognitive dysfunction among individuals undergoing rhinoplasty or septoplasty. Study Design: A randomised double-blind study. Pla...

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Outcomes of Continuous and Non-Invasive Positive Pressure Ventilation in Neonates

By Rabia Munir, Nimra Chohan, Aiman Ali Brohi, Hafiz Muhammad Aamir Yousuf, Muhammad Sohail Salat

ABSTRACT Objective: To compare the clinical outcomes of non-invasive nasal intermittent positive pressure ventilation (NIPPV) with nasal continuous positive airway pressure (NCPAP) in preterm neonates following extubation. Study Design: Descriptive, analytical study. Place and Duration of the Study:...

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CAD/CAM-Guided Vs. Manual Crown Preparation in Fixed Prosthodontics: A Randomised Controlled Trial

By Tao Huang, Han Zheng, Zhuo Chen, Qiong Sun, Lei Zhang, Fuhua Zhang

ABSTRACT Objective: To evaluate the efficacy of a novel CAD/CAM-guided crown preparation technique compared with conventional manual methods in fixed prosthodontics. Study Design: A randomised controlled trial (RCT). Place and Duration of the Study: Department of Endodontic Dentistry, Hefei Stomato...

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Effectiveness of the ARISCAT Risk Score for Predicting Postoperative Pulmonary Complications in Major Urological Surgery

By Ali Akgul, Ali Akdogan, Ahmet Besir, Ersagun Tugcugil, Sedat Saylan

ABSTRACT Objective: To evaluate the predictive power of the ARISCAT (assess respiratory risk in surgical patients in Catalonia) score for postoperative pulmonary complications (PPCs) following major urological procedures. Study Design: A descriptive study. Place and Duration of the Study: Department...


Effectiveness of Team-Based Learning Compared with Lecture-Based Learning in Clinical Medicine: A Meta-Analysis

By Bing-Rui Lu, Shu-Hong Huang, Xu-Ying Shi, Guo-Xiang Li, Qing Yin, Zhi-Gang Sun

ABSTRACT A comprehensive comparison and evaluation of the effects of team-based learning (TBL) and lecture-based learning (LBL) in clinical medical education (CME) was conducted. A thorough search was carried out over PubMed, Embase, Web of Science, and Cochrane Library databases for publications ab...


Efficacy and Safety of Antifungal Medicines in the Treatment of Invasive Aspergillosis: A Network Meta-Analysis

By Liangdong Zhu, Xun Yang, Keyu Li, Xiaolin Li, Xia Chen

ABSTRACT A frequentist network meta-analysis (NMA) was conducted to assess the efficacy and safety of voriconazole, posaconazole, isavuconazole, amphotericin B deoxycholate (AmB-D), and liposomal AmB (L-AmB) in the treatment of invasive aspergillosis (IA). This study searched PubMed, Cochrane Librar...


Challenges and Opportunities in Implementing Formative Assessment in Medical Colleges of Peshawar: A Cross-Sectional Study

By Syeda Shamal, Brekhna Jamil, Sahar Mufti, Haider Ali, Shimee Shahzadi, Liaqat Ali

ABSTRACT Objective: To explore the challenges and opportunities associated with the implementation of formative assessment (FA) practices in medical colleges of Peshawar. Study Design: A cross-sectional study. Place and Duration of the Study: Four Medical colleges, two private (Rehman Medical Colleg...


Reconstruction of the Uterine Round Ligament During Laparoscopic Totally Extraperitoneal Inguinal Hernia Repair

By Haiwei Chen, Shida Zhang, Zhe Ji, Xiong Lu, Zhendong Jiao

ABSTRACT Objective: To evaluate the safety and feasibility of a new technique for preserving the uterine round ligament (RL) during laparoscopic totally extraperitoneal (TEP) repair in female patients with inguinal hernias. Study Design: Observational study. Place and Duration of the Study: Departme...


Mixed-Phenotype Acute Leukaemia: Bridging the Gap Between Myeloid and Lymphoid Lineages

By Muhammad Zain Arshad, Muhammad Hussain, Muhammad Omair Riaz, Mustajab Alam, Muhammad Aftab Hassan, Maymoona Sohail

ABSTRACT Objective: To characterise mixed-phenotype acute leukaemia (MPAL) using flowcytometric immunophenotyping in a flow cytometric local population of Pakistan. Study Design: A descriptive, cross-sectional study. Place and Duration of the Study: Department of Immunology, Armed Forces Institute ...


Efficacy of Repeated Low-Level Red Light in the Prevention and Control of Myopia among Children and Adolescents

By Xue Zhang, Zirui Liu, Di Zhang, Zhuang Xiong

ABSTRACT Objective: To evaluate the efficacy of repeated low-intensity red light (RLRL), orthokeratology (ortho-k) lenses, and defocus spectacle lenses in controlling axial length (AL) elongation in children and adolescents with myopia. Study Design: Prospective randomised controlled trial. Place an...


Treatment of Refractory Cancer Pain with Methadone

By Xiaoting Zeng, Qianyu Wang, Weiping Zhang

ABSTRACT One-third of cancer patients currently experience cancer-related pain, significantly affecting their quality of life. Since the introduction of the World Health Organization (WHO)'s analgesic ladder, pain management has become increasingly standardised, facilitating more effective treat...


Exacerbating Crises: The Devastating Impact of Climate Change and Antibiotic Resistance on Human and Animal Health in Pakistan

By Maria Khan, Saba Khan, Shifa Basharat

ABSTRACT Antimicrobial resistance (AMR) in Pakistan and other comparable regions may be indirectly impacted by changes in the climate. The relationship between AMR and climate change is complex and multidimensional, as both factors can influence temperature and precipitation patterns, thereby a...


Glomerular Filtration Rate by Gamma Camera-Based Method: Interobserver Agreement at a Single Centre

By Rebecca Sharoon, Zaigham Salim Dar, Muhammad Atif, Zeeshan Sikandar, Raana Fatima

ABSTRACT The objective of this study was to determine interobserver agreement (IOA) in the calculation of glomerular filtration rate (GFR) by the gamma camera-based method. It was a cross-sectional prospective study carried out at the Nuclear Medical Centre, the Armed Forces Institute of Pathology, ...


Association Between Preoperative Expectations and Postoperative Satisfaction in Patients Undergoing Arthroscopic Rotator Cuff Repair

By Qilong Jiang, Yang Liu, Zhi Zhao, Yu Chen, Yu Deng

ABSTRACT The aim of this study was to determine the association between preoperative expectations (PE) and postoperative satisfaction in patients undergoing arthroscopic rotator cuff repair (ARCR). A total of 55 patients, who underwent ARCR between June 2020 and June 2023 were included in this retro...


Evaluation of Paediatric Death Pronouncement from a Resource-Limited Country

By Urooj Faisal, Marium Noor, Anwarul Haque

ABSTRACT Death pronouncement (DP) in children is quite challenging and distressing, especially for junior paediatric residents. This study aims to evaluate the implementation of the WHO international criteria for the determination of death in Paediatric patients. A retrospective chart review was con...


Cyclosporine: An Emerging Therapeutic Agent for
Paediatric Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis

By Madiha Hanif, Atiya Rahman


Thoracic Spinal Stenosis Combined with Spinal Cord Compression in the First Article: Ossification or
Sclerosis of the Ligamentum Flavum

By Hanlei Li, Wendong Xie, Lan Zhang


Complete Response in a Case of Hormone-Positive, HER2-Negative Breast Cancer Presenting with Visceral Crisis

By Gokhan Ozturk, Aysun Fatma Akkus, Tayyip Ilker Aydin


Solitary Tracheobronchopathia Osteochondroplastica with Lung Adenocarcinoma

By Yueqin Hao, Chen Jiang, Sujie Lin


RET-Rearranged Small Round Cell Sarcoma

By Binbin An, Yapeng Yao, Xin Li